Administration of nusinersen via paramedian approach for spinal muscular atrophy

Iwayama Hideyuki; Wakao Norimitsu; Kurahashi Hirokazu; Kubota Norika; Hattori Ayako; Kumagai Toshiyuki; Okumura Akihisa

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Administration of nusinersen via paramedian approach for spinal muscular atrophy

机译：通过Paramedian方法给Nusinersen管理脊髓肌萎缩方法

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Objective: To assess the success rate, procedure time, and adverse events of intrathecal administration of nusinersen via the paramedian approach in adolescents and adults with spinal muscular atrophy (SMA) associated with scoliosis.

机译：目的：通过与脊柱侧凸关联的青少年和成年人的脊柱肌萎缩（SMA）的脊柱肌肤萎缩（SMA）评估Nusinersen的成功率，程序时间和不良事件。

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来源
《Brain & Development 》 |2021年第1期| 共6页
作者
Iwayama Hideyuki; Wakao Norimitsu; Kurahashi Hirokazu; Kubota Norika; Hattori Ayako; Kumagai Toshiyuki; Okumura Akihisa;
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作者单位

Aichi Med Univ Dept Pediat Aichi Japan;

Aichi Med Univ Dept Orthoped Aichi Japan;

Aichi Med Univ Dept Pediat Aichi Japan;

Matsue Med Ctr Dept Pediat Matsue Shimane Japan;

Nagoya City Univ Dept Pediat &

Neonatol Aichi Japan;

Aichi Prefectural Colony Cent Hosp Dept Pediat Neurol Aichi Japan;

Aichi Med Univ Dept Pediat Aichi Japan;

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原文格式 PDF
正文语种 eng
中图分类神经病学与精神病学 ;
关键词
Spinal muscular atrophy; Nusinersen; Intrathecal administration; Paramedian approach; Scoliosis;

机译：脊柱肌肉萎缩;螺母;鞘内行政管理;护理人员方法;脊柱侧凸;

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1. Large deletions within the spinal muscular atrophy gene region in a patient with spinal muscular atrophy type [J] . Wei Wei, Chunyue Chen, Wenting Liu, 中国神经再生研究：英文版 . 2011 ,第023期
2. Large deletions within the spinal muscular atrophy gene region in a patient with spinal muscular atrophy type 3 [J] . Wei Wei, Chunyue Chen, Wenting Liu, 中国神经再生研究（英文版） . 2011 ,第023期
3. Progress in treatment and newborn screening for Duchenne muscular dystrophy and spinal muscular atrophy [J] . Qing Ke, Zheng-Yan Zhao, Jerry R.Mendell, 世界儿科杂志(英文版) . 2019 ,第003期
4. Progress in treatment and newborn screening for Duchenne muscular dystrophy and spinal muscular atrophy [J] . Qing Ke, Hanna Polari, Emma Ciafaloni, 世界儿科杂志（英文版） . 2019 ,第003期
5. A 5-center experience with intrathecal administration of nusinersen in SMA1 in Italy letter to the editor of european journal of pediatric neurology regarding the manuscript "single-center experience with intrathecal administration of nusinersen in children with spinal muscular atrophy type 1" written by pechmann and colleagues" [J] . Sansone V. A., Pane M., Messina S., European journal of paediatric neurology: EJPN : official journal of the European Paediatric Neurology Society . 2018 ,第4期

机译：在意大利SMA1中的SMA1中努力施用的5中心经验，致欧洲小儿科杂志的编辑，关于手稿“单中心经验，鞘内经历血液肌肉萎缩1型儿童血液肌肉萎缩1型儿童血液肌肉萎缩1型”和Pechmann和同事”
6. Intrathecal administration of nusinersen in adult and adolescent patients with spinal muscular atrophy and scoliosis: Transforaminal versus conventional approach [J] . Bortolani Sara, Stura Guido, Ventilii Giancarlo, Neuromuscular disorders: NMD . 2019 ,第10期

机译：血液肌肤萎缩和脊柱症中成人和青少年患者鞘内施用血管术和常规方法
7. Intrathecal nusinersen administration in adult spinal muscular atrophy patients with complex spinal anatomy [J] . Isabell Cordts Therapeutic advances in neurological disorders. . 2020 ,第13期

机译：血栓解剖学术脊髓肌萎缩患者鞘内凝血症患者
8. Computational modeling approach to suggest possible therapeutic interventions in spinal muscular atrophy [C] . Giulia Russo, Guanglan Zhang IEEE International Conference on Bioinformatics and Biomedicine . 2018

机译：计算建模方法，建议对脊髓性肌萎缩症进行可能的治疗干预
9. Nusinersen Treatment and Healthcare Costs in Spinal Muscular Atrophy [D] . Fox, David A. 2020

机译：血缘肌肉萎缩的螺母治疗和医疗保健成本
10. Ultrasound-guided nusinersen administration for spinal muscular atrophy patients with severe scoliosis: an observational study [O] . Jiao Zhang, Xulei Cui, Si Chen, 2021

机译：超声引导血管萎缩患者严重脊柱侧凸肌萎缩患者：观测研究
11. Administration of nusinersen via paramedian approach for spinal muscular atrophy [O] . Hideyuki Iwayama, Norimitsu Wakao, Hirokazu Kurahashi, 2021

机译：通过Paramedian肌萎缩方法管理Nusinersen
12. Columbia SMA Project: A Randomized, Control Trial of the Effects of Exercise on Motor Function and Strength in Patients with Spinal Muscular Atrophy (SMA). [R] . De Vivo, D. C. 2012

机译：哥伦比亚sma项目：运动对脊髓性肌萎缩症（sma）患者运动功能和力量影响的随机对照试验。

Administration of nusinersen via paramedian approach for spinal muscular atrophy

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