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Don't forget the heart when looking at the risk of postoperative pulmonary complications.

机译:在考虑术后发生肺部并发症的风险时,请不要忘记心脏。

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We read with great interest the recent study by Canet et al. In this investigation, based on 2,464 surgical patients, the incidence of postoperative pulmonary complications (PPCs) was 5%, with a related mortality rate at Day 30 of 19.5% (95% CI, 12.5-26.5%). Predicting risk factors for PPCs is a cornerstone of better patient management. However, reliable knowledge of PPC incidence in a broad, heterogeneous surgical population remains difficult because of nonrepresentative samples and statistical flaws. Furthermore, definitions of PPC are often not explicit and differ among studies. The recent study of Canet et al. has similarities with that of McAlister et al. Both investigations were built with a strong statistical methodology and included a large representative surgical population. Yet, the 5% incidence of PPC reported by Canet etal. is almost double the 2.7% reported by McAlister et al. This higher rate of complications observed by Canet et al. could be explained, in part, by the inclusion of emergency cases (14.2%), whereas McAlister et al. included only scheduled cases. The risk of PPC increases significantly in emergency cases.3 In addition, Canet et al. included some thoracic surgical cases. Another major difference is related to the use of different PPC definitions. The diagnostic criteria used by McAlister etal. were stricter, including supplementary therapeutic action, such as mechanical ventilation for respiratory failure, percutaneous intervention for treatment of pleural effusion, and bronchoscopic intervention for atelectasis.
机译:我们非常感兴趣地阅读了Canet等人的最新研究。在这项研究中,基于2464名外科手术患者,术后肺部并发症(PPC)的发生率为5%,第30天的相关死亡率为19.5%(95%CI,12.5-26.5%)。预测PPC的危险因素是改善患者管理的基础。但是,由于无代表性的样本和统计缺陷,在广泛的异类手术人群中对PPC发生率的可靠了解仍然很困难。此外,PPC的定义通常不明确,各研究之间也有所不同。 Canet等人的最新研究。与McAlister等人的相似之处。两项研究均采用强大的统计方法进行,并包括大量有代表性的外科手术人群。然而,Canet等报道的PPC发生率为5%。几乎是McAlister等人报道的2.7%的两倍。 Canet等人观察到这种较高的并发症发生率。可以部分解释为包括紧急情况(14.2%),而McAlister等人。仅包括计划中的案例。在紧急情况下,PPC的风险显着增加。3此外,Canet等人。包括一些胸外科手术病例。另一个主要区别与使用不同的PPC定义有关。 McAlister等使用的诊断标准。更严格,包括辅助治疗措施,如呼吸衰竭的机械通气,经胸腔积液的经皮介入治疗和肺不张的支气管镜干预。

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