Thermo and light-responsive phase change nanofibers with high energy storage efficiency for energy storage and thermally regulated on-off drug release devices

摘要

Thermo/light-responsive functionalized cellulose nanocrystal-zinc oxide (f-CNC-ZnO) nanohybrids based poly (3-hydroxybutyrate-co-3-hydroxy valerate) (PHBV) phase change nanofiber (PCF) composites with highly thermal energy storage ability were developed for controllable drug release applications. Under sunlight irradiation, the PCF composite (without f-CNC-ZnO) absorbed light and stored the thermal energy with 46.3% efficiency. An "on-off" temperature regulation of tetracycline hydrochloride (TH) release was found for PCF composites according to phase change temperature. At the temperature close to the melting point of PEG at 60 degrees C, the PCF composite with 5 wt% f-CNC-ZnO displayed a sustained release of more than 40.5 and 78.9% of tetracycline hydrochloride (TH) were released over two weeks for the 10 and 30 wt% drug loading. Thus, the PCF composites with excellent thermo/light-responsive properties and high energy storage efficiency are beneficial for promising sustainable thermal storage and drug delivery systems.