A phase I randomized controlled trial to evaluate safety and clinical effect of topically applied GSK2981278 ointment in a psoriasis plaque test

Kang E.G.; Wu S.; Gupta A.; Mackensen Y.‐L.; Siemetzki H.; Freudenberg J.M.; Wigger‐Alberti W.; Yamaguchi Y.

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A phase I randomized controlled trial to evaluate safety and clinical effect of topically applied GSK2981278 ointment in a psoriasis plaque test

机译：一期随机对照试验，以评估局部施用GSK2981278软膏在牛皮癣斑块试验中的安全性和临床效果

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来源
《British Journal of Dermatology》 |2018年第6期|共3页
作者
Kang E.G.; Wu S.; Gupta A.; Mackensen Y.‐L.; Siemetzki H.; Freudenberg J.M.; Wigger‐Alberti W.; Yamaguchi Y.;
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GlaxoSmithKlineCollegeville 1250 S. Collegeville Rd Collegeville PA 19426 U.S.A.;

GlaxoSmithKlineCollegeville 1250 S. Collegeville Rd Collegeville PA 19426 U.S.A.;

GlaxoSmithKlineCollegeville 1250 S. Collegeville Rd Collegeville PA 19426 U.S.A.;

bioskin GmbHBurchardstrasse 17 Hamburg 20095 Germany;

bioskin GmbHBurchardstrasse 17 Hamburg 20095 Germany;

GlaxoSmithKlineCollegeville 1250 S. Collegeville Rd Collegeville PA 19426 U.S.A.;

bioskin GmbHBurchardstrasse 17 Hamburg 20095 Germany;

GlaxoSmithKlineCollegeville 1250 S. Collegeville Rd Collegeville PA 19426 U.S.A.;

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原文格式 PDF
正文语种 eng
中图分类皮肤病学与性病学;
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1. A phase I randomized controlled trial to evaluate safety and clinical effect of topically applied GSK2981278 ointment in a psoriasis plaque test [J] . Kang E.G., Wu S., Gupta A., British Journal of Dermatology . 2018,第6期

机译：一期随机对照试验，以评估局部施用GSK2981278软膏在牛皮癣斑块试验中的安全性和临床效果
2. Efficacy and safety of ixekizumab for the treatment of moderate-to-severe plaque psoriasis: Results through 108 weeks of a randomized, controlled phase 3 clinical trial (UNCOVER-3) (vol 77, pg 855, 2017) [J] . Blauvelt A., Gooderham M., Iversen L. Journal of the American Academy of Dermatology . 2019,第1期

机译：Ixekizumab治疗中度至重度斑块牛皮癣的疗效和安全性：结果通过108周的随机，受控第3阶段临床试验（揭露-3）（Vol 77，PG 855,2017）
3. Efficacy and safety of ixekizumab for the treatment of moderate-to-severe plaque psoriasis: Results through 108?weeks of a randomized, controlled phase 3 clinical trial (UNCOVER-3) [J] . Andrew Blauvelt, Melinda Gooderham, Lars Iversen, Journal of the American Academy of Dermatology . 2017,第5期

机译：Ixekizumab治疗中度至重度斑块牛皮癣的疗效和安全性：结果通过108？TA周内的随机，受控第3期临床试验（未发现-3）
4. Clinical Field Trial to Evaluate the Efficacy of Topically Applied Diclofenac Liposomal Cream for the Relief of Joint Lameness in Horses [C] . Joseph J. Bertone, Randy C. Lynn, Nicholas J. Vatistas, Annual Convention of the American Association of Equine Practitioners . 2002

机译：临床田间试验，评价局部施加的双氯芬酸脂质体乳膏在马匹中关节跛足的疗效
5. Hypotensive resuscitation versus standard fluid resuscitation for the management of trauma patients in hemorrhagic shock: The safety phase of a randomized controlled trial. [D] . Morrison, C. Anne. 2009

机译：低血压复苏与标准液体复苏在失血性休克中对创伤患者的处理：一项随机对照试验的安全性阶段。
6. Treatment of plaque psoriasis with an ointment formulation of the Janus kinase inhibitor tofacitinib: a Phase 2b randomized clinical trial [O] . Kim A. Papp, Robert Bissonnette, Melinda Gooderham, 2016

机译：用Janus激酶抑制剂Tofacitinib软膏制剂治疗斑块状牛皮癣：2b期随机临床试验
7. Apremilast, an oral phosphodiesterase 4 (PDE4) inhibitor, in patients with moderate to severe plaque psoriasis: Results of a phase III, randomized, controlled trial (Efficacy and Safety Trial Evaluating the Effects of Apremilast in Psoriasis [ESTEEM] 1). [O] . Papp, Kim, Reich, Kristian, Leonardi, Craig L, 2015

机译：apremilast，一种口服磷酸二酯酶4（pDE4）抑制剂，用于中度至重度斑块状银屑病患者：III期随机对照试验的结果（评估apremilast在银屑病中的作用的功效和安全性试验[EsTEEm] 1）。

A phase I randomized controlled trial to evaluate safety and clinical effect of topically applied GSK2981278 ointment in a psoriasis plaque test

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