Prognostic Impact of the Interaction between DNMT3A mutation and Internal Tandem Duplication of the FLT3 Gene (FLT3-ITD) in Patients with De Novo Mutated NPM1 (NPM1mut) acute Myeloid Leukemia

Onate Guadalupe; Garrido Ana; Esteve Jordi; Coll Rosa; Arnan Sangerman Montserrat; Vives Susana; Sampol Antonia; Tormo Mar; Escoda Lourdes; Queipo De Llano Maria Paz; Garcia-Guinon Antoni; Bargay Joan; Salamero Olga; Aljarilla Alba; Brunet Salut; Sierra Jorge; Nomdedeu Josep; Pratcorona Marta

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Prognostic Impact of the Interaction between DNMT3A mutation and Internal Tandem Duplication of the FLT3 Gene (FLT3-ITD) in Patients with De Novo Mutated NPM1 (NPM1mut) acute Myeloid Leukemia

机译：DNMT3A突变与内部串联重复的相互作用的预后影响（FLT3-ITD）在DE Novo突变NPM1（NPM1MUT）急性髓性白血病患者中

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来源
《Blood: The Journal of the American Society of Hematology》 |2018年第novaelatreatmentappr期|共5页
作者
Onate Guadalupe; Garrido Ana; Esteve Jordi; Coll Rosa; Arnan Sangerman Montserrat; Vives Susana; Sampol Antonia; Tormo Mar; Escoda Lourdes; Queipo De Llano Maria Paz; Garcia-Guinon Antoni; Bargay Joan; Salamero Olga; Aljarilla Alba; Brunet Salut; Sierra Jorge; Nomdedeu Josep; Pratcorona Marta;
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作者单位

Autonomous Univ Barcelona Hosp Santa Creu &

St Pau Hematol Dept Barcelona Spain;

Autonomous Univ Barcelona Hosp Santa Creu &

St Pau Hematol Dept Barcelona Spain;

Hosp Clin Barcelona Hematol Dept Barcelona Spain;

Hosp Josep Trueta Inst Catala Oncol Hematol Dept Girona Spain;

Hosp Duran &

Reynals ICO LHospitalet Dept Hematol Barcelona Spain;

Hosp Badalona Germans Trias &

Pujol Barcelona Spain;

Son Espases Univ Hosp IdISBa Hematol Dept Palma De Mallorca Spain;

Inst Invest INCLIVA Hosp Clin Univ Hematol Dept Valencia Spain;

Inst Catala Oncol Tarragona Tarragona Spain;

Hosp Virgen de la Victoria Malaga Spain;

Hosp Arnau Vilanova Lleida Spain;

Hosp Sont LLatzer Palma De Mallorca Spain;

Univ Hosp Vall dHebron Dept Hematol Barcelona Spain;

Hosp Sant Pau Barcelona Spain;

Autonomous Univ Barcelona Hosp Santa Creu &

St Pau Hematol Dept Barcelona Spain;

Autonomous Univ Barcelona Hosp Santa Creu &

St Pau Hematol Dept Barcelona Spain;

Autonomous Univ Barcelona Hosp Santa Creu &

St Pau Hematol Dept Barcelona Spain;

Autonomous Univ Barcelona Hosp Santa Creu &

St Pau Hematol Dept Barcelona Spain;

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正文语种 eng
中图分类血液及淋巴系疾病;
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专利

1. Prognostic Impact of the Interaction between DNMT3A mutation and Internal Tandem Duplication of the FLT3 Gene (FLT3-ITD) in Patients with De Novo Mutated NPM1 (NPM1mut) acute Myeloid Leukemia [J] . Onate Guadalupe, Garrido Ana, Esteve Jordi, Blood: The Journal of the American Society of Hematology . 2018,第NovaelaTreatmentAppr期

机译：DNMT3A突变与内部串联重复的相互作用的预后影响（FLT3-ITD）在DE Novo突变NPM1（NPM1MUT）急性髓性白血病患者中
2. The prevalence and clinical profiles of FLT3-ITD, FLT3-TKD, NPM1, C-KIT, DNMT3A, and CEBPA mutations in a cohort of patients with de novo acute myeloid leukemia from southwest China [J] . Gou Haimei, Zhou Juan, Ye Yuanxin, Tumour biology : . 2016,第6期

机译：在中国西南部新发急性髓细胞性白血病患者队列中，FLT3-ITD，FLT3-TKD，NPM1，C-KIT，DNMT3A和CEBPA突变的患病率和临床特征
3. Analysis of FLT3-ITD and FLT3-Asp835 mutations in de novo acute myeloid leukemia: evaluation of incidence, distribution pattern, correlation with cytogenetics and characterization of internal tandem duplication from Indian population. [J] . Ahmad F, Mandava S, Das BR Cancer investigation . 2010,第1期

机译：从头进行的急性髓细胞性白血病的FLT3-ITD和FLT3-Asp835突变分析：评估印度人群的发病率，分布模式，与细胞遗传学的相关性以及内部串联复制的特征。
4. Internal Tandem Duplication of FLT3 and Activating Mutation of D835 Analyses in AML and MDS Patients [C] . C. Lo Nigro, D. Mattei, N. Mordini, European Haematology Association . 2002

机译：FLT3的内部串联复制和AML和MDS患者D835分析的激活突变
5. Comparison of FLT3 Inhibitors with the Standard Treatment for FLT3-ITD Mutated Acute Myeloid Leukemia [D] . Argetsinger, Stephanie. 2018

机译：FLT3抑制剂对FLT3-ITD突变急性髓性白血病标准治疗的比较
6. Prognostic Significance of NPM1 Mutations in the Absence of FLT3–Internal Tandem Duplication in Older Patients With Acute Myeloid Leukemia: A SWOG and UK National Cancer Research Institute/Medical Research Council Report [O] . Fabiana Ostronoff, Megan Othus, Michelle Lazenby, -1

机译：NPM1突变在老年急性髓性白血病患者中不存在FLT3-内部串联重复的预后意义：SWOG和英国国家癌症研究所/医学研究理事会的报告
7. The prognostic impact of FLT3-ITD and NPM1 mutations in patients with relapsed acute myeloid leukemia and intermediate-risk cytogenetics [O] . J How, J Sykes, M D Minden, 2013

机译：FLT3-ITD和NPM1突变对复发急性髓性白血病和中间风险细胞遗传学患者的预后影响

Prognostic Impact of the Interaction between DNMT3A mutation and Internal Tandem Duplication of the FLT3 Gene (FLT3-ITD) in Patients with De Novo Mutated NPM1 (NPM1mut) acute Myeloid Leukemia

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