Legionella pneumophila infection-mediated regulation of RICTOR via miR-218 in U937 macrophage cells

摘要

Background: Inhalation of aerosolized Legionella pneumophila, a Gram-negative bacterium, can cause severe pneumonia. During infection, L. pneumophila replicates intracellularly in macrophages. The involvement of host microRNAs (miRNAs) in L. pneumophila infection is not fully understood.