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Performance of a new oxygen delivery device for potentially infectious critically ill patients

机译:新的氧气输送装置针对潜在传染性危重病人的性能

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In patients with highly contagious diseases that are spread by respiratory droplets or air-borne particles, the use of high-flow oxygen may carry a significant risk of nosocomial transmission. We tested a new oxygen delivery device designed to address these problems by simulating 108 patients with sepsis and respiratory failure. The device being tested consisted of an airtight mask, a bacterial and viral filter, a T-shaped reservoir (50 and 100 ml) and oxygen delivery tubing connected directly to the mask. When tested with a 50-ml reservoir, a high fractional oxygen concentration was achieved: mean (SD) 0.83 (0.11) at a flow of 15 l.min-1 oxygen. The 50-ml reservoir, when compared with the 100-ml reservoir, was associated with reduced carbon dioxide rebreathing (mean (SD) inspired fractional carbon dioxide concentration 2.5 (1.0) vs 3.0 (1.1), respectively, p = 0.009) and reduced inspiratory resistive work of breathing (mean (SD) 1.0 (0.6) J.l-1 vs 1.2 (0.5) J.l -1, respectively, p = 0.028). However, rebreathing and work of breathing were relatively high if a high respiratory rate was simulated. We conclude that the novel oxygen device we describe, equipped with the 50-ml T-shaped reservoir, is suitable for potentially infectious patients with type-1 respiratory failure but without marked tachypnoea.
机译:在具有高度传染性的疾病中,这些疾病通过呼吸道飞沫或空气传播的颗粒扩散,使用高流量氧气可能会带来医院内传播的重大风险。我们模拟了108名败血症和呼吸衰竭的患者,测试了一种旨在解决这些问题的新型氧气输送装置。被测试的设备包括一个气密面罩,一个细菌和病毒过滤器,一个T形储液罐(50和100毫升)和直接连接到该面罩的氧气输送管。当使用50 ml的储罐进行测试时,获得了高的分数氧气浓度:在15 l.min-1的氧气流量下,平均值(SD)为0.83(0.11)。与100毫升储液罐相比,50毫升储液罐减少了二氧化碳的再呼吸(平均(SD)激发的分数二氧化碳浓度分别为2.5(1.0)和3.0(1.1),p = 0.009)并降低了吸气的呼吸阻力功(分别为(SD)1.0(0.6)Jl-1和1.2(0.5)Jl -1,p = 0.028)。但是,如果模拟高呼吸频率,则呼吸和呼吸功相对较高。我们得出的结论是,我们描述的新型氧气设备配备了50毫升T形储罐,适用于具有1型呼吸衰竭但无明显呼吸困难的潜在感染性患者。

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