We read with great interest the editorial by Grocott [1] and subsequent correspondence from Theiler et al. [2], and agree that brain monitoring is often not performed during anaesthesia. However, monitoring different brain functions and activities has become standard in the management of neurosurgical patients. Awake surgery, neurophys-iological control, electro-encephalog-raphy (EEG), cerebral oximetry and intracranial or tissue oxygen partial pressure measurement can provide useful information regarding global brain function in anaesthetised patients, but of all monitors, bispectral index (BIS) is the most commonly used. A large volume of research underlines its capacity to provide rapid and reliable information in various situations [3]. In general, these papers reflect changes due to hypoperfusion, reperfusion or drug administration [4, 5].
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