Re: 'Sleep disturbance and incidence of thyroid cancer in postmenopausal women. The women's health initiative'

摘要

In a recent study, Luo et al. (1) examined the associations of sleep disturbance and sleep duration with the risk of thyroid cancer in 142,933 postmenopausal women over an average of 11 years of follow-up. After adjustment for several con-founders, the hazard ratio for thyroid cancer among women with scores on the Insomnia Rating Scale (IRS) in the highest quartile (versus scores in the lowest quartile) was determined to be 1.44 (95% confidence interval: 1.01, 2.05). A subanalysis revealed that the result was significant only in nonobese women, those with a body mass index under 30. In contrast, neither a longer duration of sleep nor a shorter duration was recognized as a significant risk factor for thvroid cancer (1).