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Novel Immunotherapies for B-Cell Lymphomas and Leukemias

机译:B细胞淋巴瘤和白血病的新型免疫疗法

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摘要

Current immunotherapeutic agents under investigation have the potential to significantly expand our ability to effectively treat B-cell malignancies. New disease targets, novel strategies to deliver therapy, and advanced agents that work to manipulate the immune system are a few of the ways immunotherapy has quickly evolved. Novel targeted and immune-modifying therapies may demonstrate early potential but unique toxicities and other limitations, such as difficulties in administration, must also be acknowledged. This review provides a comprehensive assessment of the current immunotherapies under investigation against B-cell malignancies.
机译:当前正在研究的免疫治疗剂有潜力显着扩展我们有效治疗B细胞恶性肿瘤的能力。新的疾病靶标,提供治疗的新策略以及可操纵免疫系统的先进药物是免疫治疗迅速发展的几种方式。新型靶向和免疫修饰疗法可能显示出早期潜力,但也必须认识到独特的毒性和其他局限性,例如给药困难。这篇综述提供了针对B细胞恶性肿瘤的当前免疫疗法的全面评估。

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