Opacification of Hydroview intraocular lenses necessitating lens replacement

摘要

PURPOSE: We report the opacification of Hydroview intraocular lenes necessitating lens replacement. SUBJECTS AND METHODS: This study includes 9 eyes of 7 patients (4 eyes of 3 men and 5 eyes of 4 womens, 52-92 years old) who underwent lens replacement at our hospital. A clinicopathological study and speculation on the incidence of Hydroview opacification were carried over. RESULTS: All patients had hypertension and 3 had diabetes mellitus. Four eyes of 3 cases and 2 eyes of 2 cases demonstrated diabetic retinopathy and pseudoexfoliaton syndrome, respectively. Four of 6 cases, who underwent bilateral lens implantation, showed unilateral opacification. The duration from lens implantation to exchange ranged from 17 to 38 months. Slit-lamp examination revealed generalized opacification with white granular deposits on the lens optic surface, but transparency inside the optic. Three explanted lenses were stained with 1% alizarin red, and were positive for calcium in all cases. The remaining 6 lenses were analyzed with scanning electron microscopy, and showed electrondense granular deposits of 1 to 4 microm diameter. It is theorized that the incidence of Hydroview opacification and necessity of replacement were more than 3.8% and 3.6%, respectively, from the data at one hospital. CONCLUSION: Calcium deposition on Hydroview might occur in more than 3.8% of cases.