Fabrication and characterization of polymeric cellular foams for low-density computed tomography phantom applications

摘要

Computed tomography imaging phantom devices have proven to be beneficial in improving computed tomography diagnostic techniques. Though commercial phantoms are available with tissue mimicking properties, there is a lack of low-density tissue specificity and variety. This study proposes a method for the fabrication of various low-density tissue mimicking computed tomography imaging phantoms. By illustrating the fabrication technique, material properties can be shown to be controlled and assessed against characteristic computed tomography imaging properties, most particularly, the computed tomography number in Hounsfield Units. A batch cellular foaming technique was utilized on thermoplastic polyurethane with ranging heated water bath foaming times from 0.5 to 10 min to fabricate polymeric computed tomography phantoms of controlled foam material properties. Computed tomography number values were experimentally measured. Additionally, separate experimental measurements were made on the foam characteristic properties of fabricated thermoplastic polyurethane foams. A relative decreasing trend was exhibited between the foam characteristic properties of cell density, average cell size, and material density to computed tomography number.