Foundations of Evidence-Based Practice: Critical Care Trial Networks

摘要

There are various attributes of a multicenter study that are important to consider. In weighing data from a multicenter RCT versus other types of study formats, we tend to hold the RCTs findings in higher esteem because of the multicenter design, which generally displays fewer biases than do retrospective or single-center studies. Theoretically, results from a properly conducted multi-center trial should be given more weight and be more accepted than results from other types of studies. The RCT has been credited as yielding the highest level of scientific clinical credibility.