Measurement of thyroid uptake is perhaps one of the most basic procedures performed in nuclear medicine today. The uptake procedure assesses iodide trapping and organifi-cation within the gland (7). It is most commonly performed to differentiate thyroiditis from other forms of thyrotoxicosis and determine the therapeutic dose activity for hyperthyroid-ism or ablative therapy (2,3). ~(131)I- and ~(123)I-sodium iodide are the most commonly used radiopharmaceuticals for thyroid uptake determination. The assessment of the thyroid gland to take up and retain radioactive iodine is based on a ratio of the radioactive capsule (considered to be 100%) and the amount retained by the gland within a specified time period.
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