Antiretroviral Preexposure Prophylaxis for Preventing HIV Infection in High-Risk Individuals.

摘要

For some groups of patients at greater risk of HIV infection (e.g., serodiscordant partners, men who have sex with men and engage in high-risk behaviors, persons with multiple concurrent sex partners, persons who exchange sex for money), preexposure prophylaxis decreased the risk of acquiring HIV infection (number needed to treat [NNT] = 56). (Strength of Recommendation: C, based on consensus, disease-oriented evidence, usual practice, expert opinion, or case series.)