ACP recommendations for VTE prophylaxis in hospitalized patients

摘要

The decision to initiate VTE prophylaxis should be based on the patient's individual risk of thromboembolism and bleeding, and the balance of benefits versus harms. Risk factors for thromboembolism are inherited (e.g., factor V Leiden mutation, prothrombin gene mutation, protein S or C deficiency, antithrombin deficiency) or are acquired (e.g., surgery, cancer, immobilization, trauma, presence of a central venous catheter, pregnancy, medication use, congestive heart failure, chronic renal disease, antiphos-pholipid antibody syndrome, obesity, smoking, older age, history of thromboembolism). Although there are many tools for assessing thromboembolism risk, there is insufficient evidence to recommend one over the others. General evidence regarding risk factors also may be used to make decisions about the need for prophylaxis.