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首页> 外文期刊>Journal of gastroenterology >miR-324-3p promotes gastric cancer development by activating Smad4-mediated Wnt/beta-catenin signaling pathway
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miR-324-3p promotes gastric cancer development by activating Smad4-mediated Wnt/beta-catenin signaling pathway

机译：MiR-324-3P通过激活Smad4介导的Wnt /β-连环蛋白信号通路来促进胃癌发育

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摘要

Background Emerging evidence suggested that miRNAs can function as oncogenes or tumor suppressors by regulating downstream target genes. miR-324-3p has been reported to function in several carcinomas, but its role in gastric cancer (GC) is still unknown. This study aims to explore the effects of miR-324-3p on the development of GC.
机译：背景技术新兴的证据表明，MiRNA可以通过调节下游靶基因来用作癌肠病或肿瘤抑制剂。 据报道，MiR-324-3P在几种癌中起作用，但其在胃癌（GC）中的作用仍然是未知的。 本研究旨在探讨MIR-324-3P对GC发展的影响。

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  • 来源
    《Journal of gastroenterology》 |2018年第6期|共15页
  • 作者

    Sun Guang-Li; Li Zheng; Wang Wei-Zhi; Chen Zheng; Zhang Lei; Li Qing; Wei Song; Li Bo-Wen; Xu Jiang-Hao; Chen Liang; He Zhong-Yuan; Ying Kai; Zhang Xuan; Xu Hao; Zhang Dian-Cai; Xu Ze-Kuan;

  • 作者单位

    Nanjing Med Univ Affiliated Hosp 1 Dept Gen Surg 300 Guangzhou Rd Nanjing Jiangsu Peoples R;

    Nanjing Med Univ Affiliated Hosp 1 Dept Gen Surg 300 Guangzhou Rd Nanjing Jiangsu Peoples R;

    Nanjing Med Univ Affiliated Hosp 1 Dept Gen Surg 300 Guangzhou Rd Nanjing Jiangsu Peoples R;

    Vanderbilt Univ Dept Surg Med Ctr Nashville TN 37240 USA;

    Nanjing Med Univ Affiliated Hosp 1 Dept Gen Surg 300 Guangzhou Rd Nanjing Jiangsu Peoples R;

    Nanjing Med Univ Affiliated Hosp 1 Dept Gen Surg 300 Guangzhou Rd Nanjing Jiangsu Peoples R;

    Nanjing Med Univ Affiliated Hosp 1 Dept Gen Surg 300 Guangzhou Rd Nanjing Jiangsu Peoples R;

    Nanjing Med Univ Affiliated Hosp 1 Dept Gen Surg 300 Guangzhou Rd Nanjing Jiangsu Peoples R;

    Nanjing Med Univ Affiliated Hosp 1 Dept Gen Surg 300 Guangzhou Rd Nanjing Jiangsu Peoples R;

    Nanjing Med Univ Affiliated Hosp 1 Dept Gen Surg 300 Guangzhou Rd Nanjing Jiangsu Peoples R;

    Nanjing Med Univ Affiliated Hosp 1 Dept Gen Surg 300 Guangzhou Rd Nanjing Jiangsu Peoples R;

    Nanjing Med Univ Affiliated Hosp 1 Dept Gen Surg 300 Guangzhou Rd Nanjing Jiangsu Peoples R;

    Nanjing Med Univ Affiliated Hosp 1 Dept Gen Surg 300 Guangzhou Rd Nanjing Jiangsu Peoples R;

    Nanjing Med Univ Affiliated Hosp 1 Dept Gen Surg 300 Guangzhou Rd Nanjing Jiangsu Peoples R;

    Nanjing Med Univ Affiliated Hosp 1 Dept Gen Surg 300 Guangzhou Rd Nanjing Jiangsu Peoples R;

    Nanjing Med Univ Affiliated Hosp 1 Dept Gen Surg 300 Guangzhou Rd Nanjing Jiangsu Peoples R;

  • 收录信息
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类 消化系及腹部疾病;
  • 关键词

    Gastric cancer; miR-324-3p; Smad4; Wnt; Organoid;

    机译：胃癌;miR-324-3p;smad4;wnt;有机体;

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