Improvements in satisfaction with skin after treatment of facial fine lines with VYC‐12 injectable gel: Patient‐reported outcomes from a prospective study

摘要

Abstract Background VYC‐12, a hyaluronic acid injectable gel, is designed to treat fine lines and provides improvements in other skin quality attributes. A prospective study demonstrated the safety and effectiveness of VYC‐12 for the improvement of fine lines as measured by changes in skin texture. Aims To evaluate patient‐reported outcomes in subjects treated intradermally with VYC‐12 in the cheeks, forehead, and neck (optional) in the prospective study. Methods Subjects received an initial treatment of VYC‐12 (N?=?131), with a touch‐up treatment, if deemed necessary, offered 30?days later, and optional repeat treatment 9?months after initial or touch‐up treatment. Subjects completed the FACE‐Q Satisfaction With Skin scale and assessed willingness to recommend treatment to a friend at baseline, months 1, 4, 6, and 9, and month 1 after repeat treatment. Subjects also evaluated their return to normal daily social activities. Results Satisfaction with skin improved from baseline in 90.8% of subjects at month 1, 88.4% at month 4, 83.6% at month 6, 76.4% at month 9, and 91.9% at month 1 after repeat treatment ( P ??.001, all time points). At least 94% of subjects returned to normal daily social activities one day after treatment (initial, touch‐up, or repeat). More than 80% of subjects said they would recommend treatment to a friend at all time points through month 9 (97% at month 1 after repeat treatment). Conclusion Treatment with VYC‐12 significantly improved satisfaction with skin in the majority of subjects, with most subjects returning to normal activities 1?day after treatment.