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首页> 外文期刊>Journal of Computational Intelligence in Bioinformatics >SLocP Tool Box-An Integrated Platform for Predicting Sub Cellular Localization of Proteins
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SLocP Tool Box-An Integrated Platform for Predicting Sub Cellular Localization of Proteins

机译:SLOCP工具箱 - 一种预测蛋白质亚细胞定位的集成平台

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摘要

Prediction of subcellular location of a protein remains a challenging task in the field of computational biology. Several approaches, employing amino acid composition, Gene Ontology based, Evolutionary profile based, statistical techniques, and machine learning techniques, are adopted for predicting the exact location of the protein. Although, several approaches exist, there remains the problem in accurate prediction of the sub-localized protein. Moreover, to achieve this task, it has become mandatory to compare the results obtained by different approaches and analyze them manually, which has become a tedious job to perform. Hence, to overcome these difficulties, it is proposed to attempt in collating the available online subcellular localization prediction tools under a single platform to achieve the results with certainty. Thus, the SLocP tool box was developed, using PERL, that provides the user to submit the sequence either singly or in multiples, enabling for easy and quick comparison of results from various prediction server. Perhaps, this tool can be executable under both Linux and Windows platform.
机译:预测蛋白质的亚细胞位置仍然是计算生物学领域的具有挑战性的任务。采用氨基酸组合物,基于基于进化概况,统计技术和机器学习技术的几种方法,用于预测蛋白质的确切位置。尽管存在几种方法,但在亚局部化蛋白的准确预测中仍然存在问题。此外,为了实现这项任务,它已成为强制性地比较不同方法获得的结果并手动分析它们,这已成为执行繁琐的工作。因此,为了克服这些困难,建议尝试在单个平台下整理可用的在线亚细胞定位预测工具,以确定结果。因此,使用Perl开发了SLOCP工具盒,其提供用户单独或用倍数提交序列,从而能够简单快速地比较各种预测服务器的结果。也许,此工具可以在Linux和Windows平台下可执行。

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