Is postexposure prophylaxis with antiretroviral therapy necessary in cases of blood exposure through a fight when HIV-1 status is unknown?

摘要

The issue of postexposure prophylaxis -for individuals with blood exposure following percutaneous injury is raised, as this is not routinely recommended in French, European, US, NY State HIV-1 guidelines [1-4] when the source patient's HIV status is unknown. During the summer 2008 in south of France, a fight with a head injury between a barman and an unknown customer resulted in a superficial wound of the barman's forehead in the form of a scratch with a short exposure to the client's bloody broken nose. The barman, a 49-year-old Caucasian, did not consult a doctor. Four weeks later, he was hospitalized (Toulon Hospital) for fever, lymphadenopathy, weight loss and cutaneous rash.