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Numerical evaluation of bone remodelling associated with trans-femoral osseointegration implant - A 68 month follow-up study

机译:跨越股骨骨整合植入物相关的骨重塑的数值评估 - A 68个月的后续研究

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摘要

Osseointegrated trans-femoral implant is a relatively new orthopaedic anchoring method for connecting a stump with a prosthesis. Through a follow-up study of a patient over six years, significant bone remodelling has been observed. Finite element (FE) simulations were carried out to investigate the relationship between the bone remodelling and the strain re-distribution around the trans-femoral osseointegrated implant system. An initial FE model representing the original status of the femur implant assembly was created from CT scans of the subject prior to osseointegration. Follow-up X-ray images were acquired at various stages post-surgery, which allowed the changes in bone wall thickness to be measured. By updating the bone thickness in the initial model, a series of follow-up FE models were created. Representative load associated with the subject's body weight was applied to the models, and the strain re-distributions were calculated. The results showed that in order to minimise the adverse effect of bone remodelling, an osseointegration implant made by functionally gradient materials are preferred over homogeneous materials. (C) 2016 Elsevier Ltd. All rights reserved.
机译:骨整合的跨性股骨植入物是一种相对较新的矫形锚固方法,用于将树桩与假体连接。通过六年患者的后续研究,已经观察到显着的骨质重塑。进行有限元(Fe)模拟,以研究骨重塑与跨股骨骨整合植入系统周围的骨重塑与菌株重新分布之间的关系。代表股骨植入物组件的原始状态的初始FE模型是从骨整合之前的CT扫描创建的。在手术后的各个阶段获得后续X射线图像,其允许测量骨壁厚度的变化。通过更新初始模型中的骨骼厚度,创建了一系列后续FE模型。将与受试者的体重相关联的代表载荷应用于模型,并计算应变重新分布。结果表明,为了最小化骨重塑的不良反应,通过功能梯度材料制成的骨整合植入物优选在均匀材料上。 (c)2016 Elsevier Ltd.保留所有权利。

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