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首页> 外文期刊>Journal of Analytical Toxicology >The prevalence of marijuana in suspected impaired driving cases in Washington state.
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The prevalence of marijuana in suspected impaired driving cases in Washington state.

机译:华盛顿州怀疑禁止驾驶案件的大麻患病率。

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摘要

In December 2012, the possession and private use of limited quantities of marijuana and marijuana products became legal in the state of Washington. At the same time, the state's driving under the influence statutes were amended to include a per se level of 5 ng/mL delta(9)-tetrahydrocannabinol (THC) in whole blood for drivers aged 21 years and older. The aim of this study was to assess the effect of marijuana legalization on the prevalence of marijuana in suspected impaired driving cases. The prevalence of both active THC and its metabolite carboxy-THC detected in such cases pre-legalization was compared with the prevalence post-legalization. In 2009-2012, the average yearly percentage of cases positive for THC and carboxy-THC was 19.1% (range: 18.2-20.2%) and 27.9% (range: 26.3-28.6%), respectively. In 2013, the percentages had significantly increased to 24.9 and 40.0%, respectively (P < 0.05). The median THC concentration over the 5-year period ranged from 5.2 to 6.3 ng/mL, with individual concentrations ranging up to 90 ng/mL. An average of 56% of cases were at or >5 ng/mL over the 5-year period. The prevalence of alcohol and the majority of other drugs in this same population of suspected impaired drivers submitted for testing did not change during this same 5-year period-marijuana was the only drug to show such an increase in frequency. Further, this observed increase remained after the data had been normalized to account for changes in laboratory testing procedures that occurred during this time period. Future studies need be conducted to ascertain whether the observed increase has had any effect on the incidence of crashes, serious injuries and/or traffic fatalities.
机译:2012年12月,占有率和私人使用有限的大麻和大麻产品在华盛顿州成为法律。与此同时,修正了在影响阶段下的州的驾驶被修正,以包括21岁及以上的司机的全血中的5 ng / ml Delta(9)-Tetrahydrocannol(THC)。本研究的目的是评估大麻合法化对涉嫌受损驾驶案件的大麻患病率的影响。在这种情况下检测到在这种情况下检测到的活性THC及其代谢物羧基THC的患病率与合法性后的患病率进行了比较。 2009 - 2012年,THC和羧基-THC阳性病例的平均年百分比分别为19.1%(范围:18.2-20.2%)和27.9%(范围:26.3-28.6%)。 2013年,分别百分比显着增加至24.9%和40.0%(P <0.05)。 5年期间的中位数浓度范围为5.2至6.3ng / ml,单个浓度范围高达90ng / ml。在5年期间,平均56%的病例在或> 5 ng / ml。在同样的5年期间 - 大麻是唯一能够展现出频率增加的药物,在同样的疑似疑似驾驶员中持续涉嫌检测的疑似驱动因素的大多数其他药物的患病率没有变化。此外,在数据被标准化后,这种观察到的增加仍然是在此时间段内发生的实验室检测程序的变化。未来的研究需要进行以确定观察到的增加是否对崩溃,严重伤害和/或交通致命的发生率产生了任何影响。

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