NEW TWO PEBROLIDE DERIVATIVES, 14-DEACETOXY-1-DEOXYPEBROLIDE AND 7 '-HYDROXYASPERPHENAMATE ISOLATED FROM PENICILLIUM sp IFM62525

Arai Syuhei; Wakana Daigo; Itabashi Takeshi; Takeda Hisashi; Yaguchi Takashi; de Campos Takaki Galba Maria; Hosoe Tomoo

首页> 外文期刊>Heterocycles: An International Journal for Reviews and Communications in Heterocyclic Chemistry >NEW TWO PEBROLIDE DERIVATIVES, 14-DEACETOXY-1-DEOXYPEBROLIDE AND 7 '-HYDROXYASPERPHENAMATE ISOLATED FROM PENICILLIUM sp IFM62525

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NEW TWO PEBROLIDE DERIVATIVES, 14-DEACETOXY-1-DEOXYPEBROLIDE AND 7 '-HYDROXYASPERPHENAMATE ISOLATED FROM PENICILLIUM sp IFM62525

机译：新的两种蜂泥糖苷衍生物，14-乙酰氧基-1-脱氧纤维化物和7'-羟基丙烯酸盐分离出来的Penicillium SP IF62525

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New two pebrolide type sesquiterpenoids, deacetoxy-1-deoxypebrolide (1) and 7'-hydroxyisoasperphenamate (2) along with asperphenamate (3), mycophenolic acid (4) and 1-deoxypebloride (5) were isolated from Penicillium sp. IFM 62525. Their structures were established from spectroscopic and chemical method. The absolute stereochemistry of 2 was confirmed by Marfey's method. Antifungal activities of these compounds were tested and 4 showed strong activity.

机译：新的两种蜂蜜型倍二萜类化合物，Deacetoxy-1-脱氧纤维素（1）和7'-羟基异氰酸丙氨酸（2）以及含量卟啉酸盐（3），霉酚酸（4）和1-脱氧氨酰基（5）与Penicillium sp分离。 IFM 62525.它们的结构是从光谱和化学方法建立的。由Marfey的方法确认了2的绝对立体化学。测试这些化合物的抗真菌活性，4显示强活性。

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来源
《Heterocycles: An International Journal for Reviews and Communications in Heterocyclic Chemistry》 |2017年第2期|共8页
作者
Arai Syuhei; Wakana Daigo; Itabashi Takeshi; Takeda Hisashi; Yaguchi Takashi; de Campos Takaki Galba Maria; Hosoe Tomoo;
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Hoshi Univ Fac Pharmaceut Sci Dept Organ Chem Shinagawa Ku 2-4-41 Ebara Tokyo 1428501 Japan;

Hoshi Univ Fac Pharmaceut Sci Dept Organ Chem Shinagawa Ku 2-4-41 Ebara Tokyo 1428501 Japan;

Hoshi Univ Fac Pharmaceut Sci Dept Organ Chem Shinagawa Ku 2-4-41 Ebara Tokyo 1428501 Japan;

Hoshi Univ Fac Pharmaceut Sci Dept Organ Chem Shinagawa Ku 2-4-41 Ebara Tokyo 1428501 Japan;

Chiba Univ Med Mycol Res Ctr Chuo Ku 1-8-1 Inohana Chiba Chiba 2608673 Japan;

Univ Catolica Pernambuco Nucleo Pesquisas Ciencias Ambientais Rua Nunes Machado 42 Boa Vista Bloco J BR-50050590 Recife PE Brazil;

Hoshi Univ Fac Pharmaceut Sci Dept Organ Chem Shinagawa Ku 2-4-41 Ebara Tokyo 1428501 Japan;

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1. NEW TWO PEBROLIDE DERIVATIVES, 14-DEACETOXY-1-DEOXYPEBROLIDE AND 7 '-HYDROXYASPERPHENAMATE ISOLATED FROM PENICILLIUM sp IFM62525 [J] . Arai Syuhei, Wakana Daigo, Itabashi Takeshi, Heterocycles: An International Journal for Reviews and Communications in Heterocyclic Chemistry . 2017,第2期

机译：新的两种蜂泥糖苷衍生物，14-乙酰氧基-1-脱氧纤维化物和7'-羟基丙烯酸盐分离出来的Penicillium SP IF62525
2. FOUR VERRUCOSIDIN DERIVATIVES ISOLATED FROM THE HYDROTHERMAL VENT SULFUR-DERIVED FUNGUS Penicillium sp. Y-50-10 [J] . Chengqian Pan, Yutong Shi, Bihi Nazia Auckloo, Химия природных соединений . 2018,第2期

机译：从水热通气硫衍生的真菌sp中分离的四种疣状蛋白衍生物。 Y-50-10
3. Janthinolide A-B, two new 2,5-piperazinedione derivatives from the endophytic Penicillium janthinellum isolated from the soft coral Dendronephthya sp. [J] . Xue C, Li T, Deng Z, Die Pharmazie . 2006,第12期

机译：Janthinolide A-B，从软珊瑚Dendronephthya sp。分离的内生青霉菌青霉中的两种新的2,5-哌嗪二酮衍生物。
4. Potential Antibacterial Activity of Endophytic Fungi Penicillium sp. and Trichoderma sp. Derived From Mangrove Ceriops Tagal (Perr.) C.B.Robb and Bruguiera sp. [C] . Yuli Haryani, Rahmiwati Hilma, Noviza Delfira, Universitas Riau International Conference on Science and Environment . 2020

机译：内生真菌青霉素SP的潜在抗菌活性。和trichoderma sp。来自红树林Ceriops Tagal（Perr。）C.B.Robb和Bruguiera Sp。
5. Characterization and Geochemistry of Novel Bacterium, Gen. Nov., Sp. Nov., Anaeropaleothermus hephaestusseraphensis Strain Siuc-3, Isolated 3.2 Kilometers Underground From the Driefontein Goldmine, South Africa [D] . Horton, Adam 2019

机译：新型细菌的表征和地球化学，Gen。Nov.，Sp。十一月，Anaeropaleothermus hephaestusseraphensis菌株Siuc-3，离地下3.2公里，位于南非Driefontein金矿
6. Dimeric 14-Benzoquinone Derivatives with Cytotoxic Activities from the Marine-Derived Fungus Penicillium sp. L129 [O] . Hui-Min Zhang, Chuan-Xia Ju, Gang Li, 2019

机译：具有海洋毒性真菌青霉菌sp。的细胞毒活性的二聚14-苯醌衍生物。 L129
7. Penicillium araracuarense sp nov., Penicillium elleniae sp nov., Penicillium penarojense sp nov., Penicillium vanderhammenii sp nov and Penicillium wotroi sp nov., isolated from leaf litter [O] . Houbraken, J., Lopez-Quintero, Carlos A., Frisvad, J.C., 2011

机译：从叶垃圾中分离出来的青霉青霉，黑青霉，青霉青霉，vanderhammenii青霉和wotroi青霉。

NEW TWO PEBROLIDE DERIVATIVES, 14-DEACETOXY-1-DEOXYPEBROLIDE AND 7 '-HYDROXYASPERPHENAMATE ISOLATED FROM PENICILLIUM sp IFM62525

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