Survival Disparities by Race and Ethnicity in Early Esophageal Cancer

摘要

Background Survival outcome disparities among esophageal cancer patients exist, but are not fully understood. Aims We used the Surveillance, Epidemiology, and End Results (SEER)-Medicare linked database to determine whether survival differences among racial/ethnic patient populations persist after adjusting for demographic and clinical characteristics. Methods Our study included T1-3N0M0 adenocarcinoma and squamous cell cancer patients diagnosed between 2003 and 2011. We compared survival among two racial/ethnic patient subgroups using Cox proportional hazards methods, adjusting for age, sex, histology, marital status, socioeconomics, SEER region, comorbidities, T stage, tumor location, diagnosis year, and treatment received. Results Among 2025 patients, 87.9% were White and 12.1% were Nonwhite. Median survival was 18.7?months for Whites vs 13.8?months for Nonwhites ( p ?=?0.01). In the unadjusted model, Nonwhite patients had higher risk of mortality (HR?=?1.29, 95% CI 1.11–1.49, p ?