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首页> 外文期刊>Diagnostic microbiology and infectious disease >Molecular characteristics of extended-spectrum β-lactamase-producing Escherichia coli in Japan: Emergence of CTX-M-15-producing E. coli ST131
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Molecular characteristics of extended-spectrum β-lactamase-producing Escherichia coli in Japan: Emergence of CTX-M-15-producing E. coli ST131

机译：日本延长光谱β-内酰胺酶大肠杆菌的分子特征：CTX-M-15产生大肠杆菌ST131的出现

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摘要

We investigated the molecular characteristics of ESBL-producing Escherichia coli in Japan. A total of 101 clinical isolates of ESBL-positive E. coli collected in Japan between June 2008 and November 2009 were studied. Among the 101 strains, 97 were positive for CTX-M, while 47 and two were positive for TEM and SHV, respectively. Sequencing revealed that CTX-M-14 was most common (49/101), followed by CTX-M-27 (22/101) and CTX-M-15 (8/101). Based on MLST data, seven of eight CTX-M-15 producers belonged to ST131. This is the first report about clinical isolates of E. coli ST131 possessing CTX-M-15 in Japan.
机译：我们调查了日本Esbl-生产的Escherichia Coli的分子特征。 研究了2008年6月至2009年6月在日本收集的ESBL阳性大肠杆菌的101分离物。 在101株菌株中，97次为CTX-M阳性，而47和2分别为TEM和SHV阳性。 测序显示CTX-M-14最常见（49/101），其次是CTX-M-27（22/101）和CTX-M-15（8/101）。 基于MLST数据，八个CTX-M-15生产商中的七个属于ST131。 这是关于在日本拥有CTX-M-15的大肠杆菌ST131的临床分离株的第一个报告。

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    KurodaH.; YanoH.; HirakataY.; AraiK.; EndoS.; KanamoriH.; YamamotoH.; IchimuraS.; OgawaM.; ShimojimaM.; KomatsuM.; JonaiT.; ItagakiS.; NonomiyaY.; SuwabeA.; KakuM.;

  • 作者单位

    Department of Infection Control and Laboratory Diagnostics Tohoku University Graduate School of;

    Department of Infection Control and Laboratory Diagnostics Tohoku University Graduate School of;

    Dept. of C-MERMAID Tohoku University Graduate School of Medicine Sendai 980-8574 Japan;

    Dept. of C-MERMAID Tohoku University Graduate School of Medicine Sendai 980-8574 Japan;

    Department of Infection Control and Laboratory Diagnostics Tohoku University Graduate School of;

    Department of Infection Control and Laboratory Diagnostics Tohoku University Graduate School of;

    Department of Internal Medicine Taro Clinic Miyako City Miyako Iwate 027-0305 Japan;

    Department of Bacteriology BML Inc. Kawagoe Saitama 350-1101 Japan;

    Department of Bacteriology BML Inc. Kawagoe Saitama 350-1101 Japan;

    Department of Bacteriology BML Inc. Kawagoe Saitama 350-1101 Japan;

    Department of Clinical Laboratory Miyagi Medical Association Kenko Center Sendai 983-0832 Japan;

    Department of Clinical Laboratory Iwate prefectural Miyako Hospital Miyako Iwate 027-0096 Japan;

    Department of Clinical Laboratory Morioka Medical Laboratories Morioka Iwate 020-0841 Japan;

    Department of Clinical Laboratory Iwate Medical University Hospital Morioka Iwate 020-8505 Japan;

    Department of Clinical Laboratory Iwate Medical University Hospital Morioka Iwate 020-8505 Japan;

    Department of Infection Control and Laboratory Diagnostics Tohoku University Graduate School of;

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  • 正文语种 eng
  • 中图分类 传染病;
  • 关键词

    CTX-M-15; ESBLs; Escherichia coli;

    机译：CTX-M-15;ESBLS;大肠杆菌;

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