Differentiating PTSD from anxiety and depression: Lessons from the ICD‐11 PTSD diagnostic criteria

Barbano Anna C.; der Mei Willem F.; deRoon‐Cassini Terri A.; Grauer Ettie; Lowe Sarah Ryan; Matsuoka Yutaka J.; ODonnell Meaghan; Olff Miranda; Qi Wei; Ratanatharathorn Andrew; Schnyder Ulrich; Seedat Soraya; Kessler Ronald C.; Koenen Karestan C.; Shalev Arieh Y.; the International Consortium to Prevent PTSD

摘要

Objective >Posttraumatic stress disorder (PTSD) is frequently associated with depression and anxiety, but the nature of the relationship is unclear. By removing mood and anxiety diagnostic criteria, the 11th edition of the International Classification of Diseases (ICD‐11) aims to delineate a distinct PTSD phenotype. We examined the effect of implementing ICD‐11 criteria on rates of codiagnosed depression and anxiety in survivors with recent PTSD. </section> <section xml:id="da22881-sec-0020"> <title type="main">Method >Participants were 1,061 survivors of traumatic injury admitted to acute care centers in Israel. ICD‐10 and ICD‐11 diagnostic rules were applied to the Clinician‐Administered PTSD Scale for DSM‐IV. Co‐occurring disorders were identified using the Structured Clinical Interview for DSM‐IV (SCID). Depression severity was measured by the Beck Depression Inventory‐II (BDI‐II). Assessments were performed 0–60 (“wave 1”) and 90–240 (“wave 2”) days after trauma exposure. </section> <section xml:id="da22881-sec-0030"> <title type="main">Results > Participants identified by ICD‐11 PTSD criteria were equally or more likely than those identified by the ICD‐10 alone to meet depression or anxiety disorder diagnostic criteria (for wave 1: depressive disorders, OR?[odds ratio]?=?1.98, 95% CI?[confidence interval] =?[1.36, 2.87]; anxiety disorders, OR?=?1.04, 95% CI?=?[0.67, 1.64]; for wave 2: depressive disorders, OR?=?1.70, 95% CI?=?[1.00, 2.91]; anxiety disorders, OR?=?1.04, 95% CI?=?[0.54, 2.01]). ICD‐11 PTSD was associated with higher BDI scores ( M?=? 23.15?vs. 17.93, P? ?0.001 for wave 1; M? =?23.93?vs. 17.94, P?< </span> <span class="z_kbtn z_kbtnclass hoverxs" style="display: none;">展开▼</span> </div> <div class="translation abstracttxt"> <span class="zhankaihshouqi fivelineshidden" id="abstract"> <span>机译：</span><Abstract Type =“Main”XML：Lang =“en”> <第XML：ID =“DA22881-SEC-0010”> <标题类型=“MAIN”>目标</标题> >后功能应激障碍（PTSD ）经常与抑郁和焦虑有关，但这种关系的性质尚不清楚。通过消除情绪和焦虑诊断标准，第11版的疾病分类（ICD-11）旨在描绘不同的PTSD表型。我们审查了在最近的PTSD中实施ICD-11关于Codiagnosed抑郁和焦虑率的效果。</ p> </ section> <section XML：ID =“DA22881-SEC-0020”> <标题类型=“主要“>方法</标题> >参与者是以色列急性护理中心的创伤损伤幸存者1,061兴奋剂。将ICD-10和ICD-11诊断规则应用于DSM-IV的临床医生的PTSD规模。使用对DSM-IV（SCID）的结构化临床访谈来确定共同发生的疾病。抑郁严重程度由Beck抑郁症IIM（BDI-II）衡量。在创伤暴露后进行0-60（“波1”）和90-240（“波2”）的评估。</ p> </段> <第XML：ID =“DA22881-SEC-0030”> <标题类型=“main”>结果</标题> </标题> </标题>由ICD-11第四个标准标识的参与者同等或更可能由ICD-10单独鉴定以满足抑郁或焦虑症诊断标准（对于WAVE 1：抑郁症，或？[赔率比]？=？1.98,95％CI？[置信区间] =？[1.36,2.87];焦虑障碍，或？=？1.04,95％CI？=？[0.67,1.64] ;对于波2：抑郁症，或？=？1.70,95％CI？=？[1.00,2.91];焦虑障碍，或？=？1.04,95％CI？=？[0.54,2.01]）。 ICD-11 PTSD与更高的BDI分数相关（ m？=Δ=Δ=Δvs.17.93，p≤≤0.0.001，对于波1; m？ </ i> =？23.93？vs。17.94， p？< </span> <span class="z_kbtn z_kbtnclass hoverxs" style="display: none;">展开▼</span> </div> </div> <div class="record"> <h2 class="all_title" id="enpatent33" > 著录项</h2> <ul> <li> <span class="lefttit">来源</span> <div style="width: 86%;vertical-align: text-top;display: inline-block;"> <a href='/journal-foreign-32884/'>《Depression and anxiety 》</a> <b style="margin: 0 2px;">|</b><span>2019年第6期</span><b style="margin: 0 2px;">|</b> <span>共9页</span> </div> </li> <li> <div class="author"> <span class="lefttit">作者</span> <p id="fAuthorthree" class="threelineshidden zhankaihshouqi"> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Barbano Anna C.&option=202" target="_blank" rel="nofollow">Barbano Anna C.;</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=der Mei Willem F.&option=202" target="_blank" rel="nofollow">der Mei Willem F.;</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=deRoon‐Cassini Terri A.&option=202" target="_blank" rel="nofollow">deRoon‐Cassini Terri A.;</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Grauer Ettie&option=202" target="_blank" rel="nofollow">Grauer Ettie;</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Lowe Sarah Ryan&option=202" target="_blank" rel="nofollow">Lowe Sarah Ryan;</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Matsuoka Yutaka J.&option=202" target="_blank" rel="nofollow">Matsuoka Yutaka J.;</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=ODonnell Meaghan&option=202" target="_blank" rel="nofollow">ODonnell Meaghan;</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Olff Miranda&option=202" target="_blank" rel="nofollow">Olff Miranda;</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Qi Wei&option=202" target="_blank" rel="nofollow">Qi Wei;</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Ratanatharathorn Andrew&option=202" target="_blank" rel="nofollow">Ratanatharathorn Andrew;</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Schnyder Ulrich&option=202" target="_blank" rel="nofollow">Schnyder Ulrich;</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Seedat Soraya&option=202" target="_blank" rel="nofollow">Seedat Soraya;</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Kessler Ronald C.&option=202" target="_blank" rel="nofollow">Kessler Ronald C.;</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Koenen Karestan C.&option=202" target="_blank" rel="nofollow">Koenen Karestan C.;</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Shalev Arieh Y.&option=202" target="_blank" rel="nofollow">Shalev Arieh Y.;</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=the International Consortium to Prevent PTSD&option=202" target="_blank" rel="nofollow">the International Consortium to Prevent PTSD;</a> </p> <span class="z_kbtnclass z_kbtnclassall hoverxs" id="zkzz" style="display: none;">展开▼</span> </div> </li> <li> <div style="display: flex;"> <span class="lefttit">作者单位</span> <div style="position: relative;margin-left: 3px;max-width: 639px;"> <div class="threelineshidden zhankaihshouqi" id="fOrgthree"> <p>Department of PsychiatryNew York University School of MedicineNew York New York;</p> <p>Department of PsychiatryNew York University School of MedicineNew York New York;</p> <p>Department of SurgeryMedical College of WisconsinMilwaukee Wisconsin;</p> <p>Department of PsychiatryNew York University School of MedicineNew York New York;</p> <p>Department of PsychologyMontclair State UniversityMontclair New Jersey;</p> <p>Division of Health Care ResearchNational Cancer Center JapanTokyo Japan;</p> <p>Pheonix AustraliaThe University of MelbourneParkville Australia;</p> <p>Department of Psychiatry Amsterdam UMCUniversity of AmsterdamAmsterdam The Netherlands;</p> <p>Department of PsychiatryNew York University School of MedicineNew York New York;</p> <p>Department of EpidemiologyColumbia University Mailman School of Public HealthNew York New York;</p> <p>Department of PsychiatryUniversity of ZurichZürich Switzerland;</p> <p>Department of PsychiatryStellenbosch UniversityCape Town South Africa;</p> <p>Department of Health Care PolicyHarvard Medical SchoolBoston Massachusetts;</p> <p>Department of EpidemiologyHarvard T.H. Chan School of Public HealthBoston Massachusetts;</p> <p>Department of PsychiatryNew York University School of MedicineNew York New York;</p> </div> <span class="z_kbtnclass z_kbtnclassall hoverxs" id="zhdw" style="display: none;">展开▼</span> </div> </div> </li> <li> <span class="lefttit">收录信息</span> <span style="width: 86%;vertical-align: text-top;display: inline-block;"></span> </li> <li> <span class="lefttit">原文格式</span> <span>PDF</span> </li> <li> <span class="lefttit">正文语种</span> <span>eng</span> </li> <li> <span class="lefttit">中图分类</span> <span>R749.72; </span> </li> <li class="antistop"> <span class="lefttit">关键词</span> <p style="width: 86%;vertical-align: text-top;"> <a style="color: #3E7FEB;" href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=anxiety disorders&option=203" rel="nofollow">anxiety disorders;</a> <a style="color: #3E7FEB;" href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=comorbidity&option=203" rel="nofollow">comorbidity;</a> <a style="color: #3E7FEB;" href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=depressive disorders&option=203" rel="nofollow">depressive disorders;</a> <a style="color: #3E7FEB;" href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=nosology&option=203" rel="nofollow">nosology;</a> <a style="color: #3E7FEB;" href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=posttraumatic stress disorder&option=203" rel="nofollow">posttraumatic stress disorder;</a> </p> <div class="translation"> 机译：焦虑症;合并症;抑郁症;病理学;诊断; 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S. </a> <span>1997</span> </span> </div> <p class="zwjiyix translation" style="max-width: initial;height: auto;word-break: break-all;white-space: initial;text-overflow: initial;overflow: initial;"> <span>机译：DsmpTsD III-R DsmpTsD的管理，评分，程序手册IV。创伤后应激障碍的结构符合Dsm-III-R Dsm-IV诊断标准</span> </p> </li> </ul> <ul style="display: none;"> <li> <div> <b>1. </b><a class="enjiyixqcontent" href="/academic-journal-cn_sichuan-mental-health_thesis/0201277873734.html">ICD-11与DSM-5关于焦虑障碍诊断标准的异同</a> <b>[J]</b> <span> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=肖茜&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor"> . 肖茜</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=张道龙&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">,张道龙</a> <span> <a href="/journal-cn-6248/" target="_blank" rel="nofollow" class="tuijian_authcolor"> . 四川精神卫生 </a> </span> <span> . 2020</span><span> ,第001期</span> </span> </div> </li> <li> <div> <b>2. </b><a class="enjiyixqcontent" href="/academic-journal-cn_journal-heze-medical-college_thesis/0201235656712.html">心理护理干预对创伤应激障碍患者焦虑抑郁症身心及细胞因子的影响</a> <b>[J]</b> <span> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=吴长然&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor"> . 吴长然</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=高涛&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">,高涛</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=李晓波&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">,李晓波</a> <span> <a href="/journal-cn-12090/" target="_blank" rel="nofollow" class="tuijian_authcolor"> . 菏泽医学专科学校学报 </a> </span> <span> . 2017</span><span> ,第002期</span> </span> </div> </li> <li> <div> <b>3. </b><a class="enjiyixqcontent" href="/academic-journal-cn_journal-clinical-psychiatry_thesis/0201237158722.html">玉树地震后罹患创伤后应激障碍、焦虑症和抑郁症调查</a> <b>[J]</b> <span> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=董强利&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor"> . 董强利</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=叶兰仙&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">,叶兰仙</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=张玉堂&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">,张玉堂</a> <span> <a href="/journal-cn-6241/" target="_blank" rel="nofollow" class="tuijian_authcolor"> . 临床精神医学杂志 </a> </span> <span> . 2014</span><span> ,第002期</span> </span> </div> </li> </ul> <ul style="display: none;"> <li> <div> <b>1. </b><a class="enjiyixqcontent" href="/patent-detail/061202827930.html">用于检测和监测用于创伤后应激障碍（PTSD）的诊断生物标志物以及用于区分自杀式与非自杀式障碍的试剂盒</a> <b>[P]</b> . <span> 中国专利： CN103959067B </span> <span> . 2018.04.24</span> </div> </li> <li> <div> <b>2. </b><a class="enjiyixqcontent" href="/patent-detail/06120102699029.html">用于检测和监测用于创伤后应激障碍(PTSD)的诊断生物标志物以及用于区分自杀式与非自杀式障碍的方法和试剂盒</a> <b>[P]</b> . <span> 中国专利： CN103959067A </span> <span> . 2014-07-30</span> </div> </li> <li> <div> <b>3. </b><a class="enjiyixqcontent" href="/patent-detail/06130401029077.html">PROCESSES AND KITS TO DETECT AND MONITOR FOR DIAGNOSTIC BIOMARKERS FOR POST TRAUMATIC STRESS DISORDER (PTSD) AND TO DIFFERENTIATE BETWEEN SUICIDAL AND NON-SUICIDAL FORM OF THE DISORDER</a> <b>[P]</b> . <span> 外国专利：  AU2018201249B2 </span> <span> . 2020-05-14</span> </div> <p class="zwjiyix translation" style="max-width: initial;height: auto;word-break: break-all;white-space: initial;text-overflow: initial;overflow: initial;"> <span>机译：创伤后应激障碍（PTSD）的诊断性生物标志物的检测和监测以及区分疾病的自杀性和非自杀性的过程和工具 </span> </p> </li> <li> <div> <b>4. </b><a class="enjiyixqcontent" href="/patent-detail/06130406269234.html">PROCESSES AND KITS TO DETECT AND MONITOR FOR DIAGNOSTIC BIOMARKERS FOR POST TRAUMATIC STRESS DISORDER (PTSD) AND TO DIFFERENTIATE BETWEEN SUICIDAL AND NON-SUICIDAL FORM OF THE DISORDER</a> <b>[P]</b> . <span> 外国专利：  AU2018201249A1 </span> <span> . 2018-03-15</span> </div> <p class="zwjiyix translation" style="max-width: initial;height: auto;word-break: break-all;white-space: initial;text-overflow: initial;overflow: initial;"> <span>机译：创伤后应激障碍（PTSD）的诊断性生物标志物的检测和监测以及区分疾病的自杀性和非自杀性的过程和工具 </span> </p> </li> <li> <div> <b>5. </b><a class="enjiyixqcontent" href="/patent-detail/06130406355743.html">Processes and kits to detect and monitor for diagnostic biomarkers for post traumatic stress disorder (PTSD) and to differentiate between suicidal and non-suicidal form of the disorder</a> <b>[P]</b> . <span> 外国专利：  AU2012308305B2 </span> <span> . 2017-11-23</span> </div> <p class="zwjiyix translation" style="max-width: initial;height: auto;word-break: break-all;white-space: initial;text-overflow: initial;overflow: initial;"> <span>机译：用于检测和监测创伤后应激障碍（PTSD）的诊断生物标志物并区分该疾病的自杀形式和非自杀形式的过程和试剂盒 </span> </p> </li> </ul> 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