BACTERIAL CONSTITUENTS .70. BIOGENESIS OF THE PYOVERDIN CHROMOPHORE

摘要

After growing Pseudomonas aeruginosa in the presence of 2,4-[4-N-15]-diaminobutyric acid (Dab) its incorporation into the quinoline chromophore of the pyoverdin produced by this bacterium could be shown by mass and NMR-spectroscopic techniques. In combination with earlier results it can thus be stated that the precursor of the chromophore is a condensation product of L-Dab and D-Phe or D-Tyr. A synthesis for [4-N-15]-Dab is described. [References: 21]