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Treated and treatment-naive alcoholics come from different populations.

机译:经过治疗和未经治疗的酗酒者来自不同人群。

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In most research on alcoholism, convenience samples of individuals who have been in some type of treatment are used. Berkson's fallacy results when the associations found in studies of select samples are incorrectly presumed to apply to all alcoholics (i.e., including untreated alcoholics in the general population). In the current study, we examined whether treated and untreated alcoholics have similar early alcohol use histories by comparing abstinent alcoholics (treated and sober at least 6 months) with treatment-naive alcoholics (active drinkers). We studied 14 pairs of women and 25 pairs of men matched on the age at which they first met criteria for heavy alcohol use (women, 80 drinks per month; men, 100 drinks per month). The timeline follow-back interview method was used to gather retrospective alcohol use information. Alcohol dose and duration of use were subsequently computed for two intervals: (1) time between the person's first drink and date at which the person met criteria for heavy drinking and (2) period between when criteria for heavy drinking were met and current age of the treatment-naive person from each pair. During the period before the matching "heavy drinking" criteria were met, alcohol dose did not differ between groups. In the period after criteria for heavy alcohol use were met, in comparison with treatment-naive alcoholics, the treated alcoholics had higher average and peak alcohol doses. We rejected the hypothesis that the treatment-naive alcoholics and the treated alcoholics have similar alcohol use trajectories over time, with the treatment-naive sample simply being observed earlier in its alcohol use histories. Instead, we concluded that the two groups come from different populations with regard to alcohol use. In fact, the treated alcoholics had alcohol doses more than 50% higher than those of treatment-naive alcoholics in the years just after they began drinking heavily. This finding supports the suggestion that results from studies of alcoholics in treatment or aftertreatment (i.e., most studies of alcoholics) cannot be generalized to untreated individuals (who make up the majority of alcoholics).
机译:在大多数酒精中毒研究中,都使用经过某种治疗的个体的方便样本。如果在某些样本研究中发现的关联被错误地推定为适用于所有酗酒者(即包括普通人群中未经治疗的酗酒者),那么伯克森的谬误就是结果。在当前的研究中,我们通过比较戒酒者(治疗和清醒至少6个月)与未接受过治疗的饮酒者(积极饮酒者)的关系,检查了已治疗和未治疗的酗酒者是否具有相似的早期饮酒史。我们研究了14对女性和25对男性,他们的年龄符合首次重度使用酒精的标准(女性每月80杯饮品;男性每月100杯饮品)。时间线跟踪采访方法用于收集回顾性饮酒信息。随后以两个时间间隔计算酒精剂量和使用时间:(1)该人首次饮酒与该人达到重度饮酒标准的日期之间的时间,以及(2)达到重度饮酒标准至当前年龄之间的时间。每对都没有治疗的人。在符合“大量饮酒”标准之前的一段时间内,两组之间的酒精剂量没有差异。在满足重度酒精使用标准的时期内,与未治疗的酒精中毒者相比,治疗的酒精中毒者的平均酒精剂量和峰值酒精剂量更高。我们拒绝了这样的假设,即未经治疗的酗酒者和经治疗的酗酒者随时间推移具有相似的酒精使用轨迹,而未经治疗的样本只是在其酒精使用历史中较早地观察到。相反,我们得出的结论是,这两组人在酒精使用方面来自不同的人群。实际上,在刚开始大量饮酒后的几年中,经过治疗的酒精饮料的酒精剂量比未经治疗的酒精饮料的酒精剂量高50%以上。这一发现支持这样的建议,即在治疗或后处理中进行酒精滥用研究的结果(即大多数酒精中毒研究)不能推广到未经治疗的个体(占大多数酒精中毒者)。

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