Congenital cystic lesions of the biliary tree (American Journal of Roentgenology (2012), 198 (825-835))

摘要

None of these randomized controlled trials (RCTs) were designed to separately assess the effect of screening women ages 40-49 years. Early subset analyses of this younger age group found no statistically significant benefit. When mortality reduction finally became apparent on longer-term follow-up, it was at first smaller and appeared later after the screening process than that for older women. The explanations for these initially disparate results for younger women included their lower breast cancer incidence rate, insufficient numbers of younger women in the trials, their faster breast cancer growth rates requiring shorter screening intervals, and their denser breasts making mammo-graphic detection more difficult.