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Predictors of unfavorable thermal outcome during newborn emergency retrievals

机译:新生儿紧急检索过程中热结果不利的预测因素

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Objective: Maintenance of normal body temperature is a challenge during transports. We aimed to identify predisposing factors for unfavorable thermal outcome during emergency retrievals of neonates. Methods: Demographic data and clinical variables for transports performed over a 2-year period were extracted from the Newborn Emergency Transport Service (Victoria, Australia) database. Arrival temperatures outside normothermia (36.5°-37.5°C) were defined as an unfavorable outcome. Results: Normothermia on arrival at the receiving hospital was achieved in 78% of 1,261 transports. The strongest predictor of unfavorable thermal outcome was an abnormal temperature at the start of the retrieval (odds ratio [OR] = 8.04; 95% confidence interval [CI], 5.91-10.95; P < .001) followed by very low weight on transport (< 1,500 g; OR = 2.49; 95% CI, 1.63-3.80; P < .001) and respiratory support (OR = 1.81; 95% CI, 1.29-2.54; P = .001). Medications (eg, inotropes and sedation/muscle relaxation) or central/peripheral venous/arterial lines were not significant predictors of outcome when temperature at retrieval start, weight at transport, and respiratory support were adjusted as cofactors. Mode of transport (road, fixed wing, or rotary wing aircraft) and outside temperature were not associated with thermal outcome. Conclusion: Abnormal temperature at the start of the retrieval, very low transport weight, and respiratory support were strong predictors of unfavorable thermal outcome during neonatal emergency transports.
机译:目的:在运输过程中维持正常体温是一项挑战。我们的目的是找出新生儿紧急抢救中不利的热结果的诱发因素。方法:从新生儿应急运输服务(澳大利亚维多利亚州)数据库中提取了为期2年的运输的人口统计学数据和临床变量。超出常温(36.5°-37.5°C)的到达温度被定义为不利的结果。结果:在1,261辆运输工具中,有78%达到了入院时的正常体温。不利的热结果的最强预测因子是检索开始时温度异常(几率[OR] = 8.04; 95%置信区间[CI],5.91-10.95; P <.001),然后运输时重量很低(<1,500克; OR = 2.49; 95%CI,1.63-3.80; P <.001)和呼吸支持(OR = 1.81; 95%CI,1.29-2.54; P = .001)。当将恢复开始时的温度,运输时的体重和呼吸支持作为辅助因素进行调整时,药物(例如,正性肌力药和镇静/肌肉松弛)或中心/周围静脉/动脉线不是预后的重要预测指标。运输方式(公路,固定翼或旋转翼飞机)和外界温度与热结果无关。结论:检索开始时体温异常,极低的运输重量和呼吸支持是新生儿紧急运输期间热预后不良的有力预测指标。

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