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首页> 外文期刊>Tropical Medicine and International Health: TM and IH >Factors for incomplete adherence to antiretroviral therapy including drug refill and clinic visits among older adults living with human immunodeficiency virus – cross‐sectional study in South Africa
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Factors for incomplete adherence to antiretroviral therapy including drug refill and clinic visits among older adults living with human immunodeficiency virus – cross‐sectional study in South Africa

机译:不完全粘附对抗逆转录病毒治疗的因素,包括患有人类免疫缺陷病毒的老年人的药物补充和诊所访问 - 南非的横截面研究

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Abstract Objectives To assess adherence outcomes to antiretroviral therapy ( ART ) of recipients ≥50 years in Soweto, South Africa. Methods This was a secondary data analysis for a cross‐sectional study at two HIV clinics in Soweto. Data on ART adherence and covariates were gathered through structured interviews with HIV 878 persons living with HIV ( PLHIV ) receiving ART . Logistic regression analysis was used to assess associations. Results PLHIV ≥50 years ( n = 103) were more likely to miss clinic visits during the last six months than PLHIV aged 25–49 ( OR 2.15; 95% CI 1.10–4.18). PLHIV ≥50 years with no or primary‐level education were less likely to have missed a clinic visit during the last six months than PLHIV with secondary‐ or tertiary‐level education in the same age category ( OR 0.3; 95% CI 0.1–1.1), as were PLHIV who did not disclose their status ( OR 0.2; 95% CI 0–1.1). There was no evidence of increased risk for non‐adherence to ART pills and drug refill visits among older PLHIV . Conclusion Missing a clinic visit was more common among older PLHIV who were more financially vulnerable. Further studies are needed to verify these findings and identify new risk factors associated with ART adherence.
机译:摘要目的,评估南非索韦托受伤者≥50年的抗逆转录病毒治疗(ART)的抗逆转录病毒治疗(艺术)。方法这是索韦托两种HIV诊所的横截面研究的二级数据分析。通过与艾滋病毒(PLHIV)接受艺术的艾滋病毒878人的艾滋病毒878人进行了结构性访谈,收集了艺术遵守和协变量的数据。 Logistic回归分析用于评估关联。结果≥50年(n = 103)更有可能在过去六个月比25-49岁(或2.15; 95%CI 1.10-4.18)中持续的六个月内丧失诊所访问。在过去六个月内,不太可能在过去六个月中错过了诊所访问的Plhiv≥50年,而在同一年龄类别(或0.3; 95%CI 0.1-1.1 ),普遍没有透露其状态(或0.2; 95%CI 0-1.1)。没有证据表明不遵守艺术丸的风险和较老的Plhiv之间的药物补充。结论缺少诊所访问在更加经济上脆弱的老年人中更常见。需要进一步的研究来验证这些调查结果并确定与艺术遵守相关的新风险因素。

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