Validation of an Isavuconazole High-Performance Liquid Chromatography Assay in Plasma for Routine Therapeutic Drug Monitoring Applications

Mueller Silke C.; Karasch Ilona; Lakner Johannes; Wacke Rainer

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Validation of an Isavuconazole High-Performance Liquid Chromatography Assay in Plasma for Routine Therapeutic Drug Monitoring Applications

机译：验证血浆中血浆中常规治疗药物监测应用中的血浆中高效液相色谱法测定

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摘要

Background: Isavuconazole is a triazole antifungal agent for treatment of invasive aspergillosis and mucormycosis. At present, it is unclear whether a therapeutic drug monitoring (TDM) of isavuconazole would be necessary. The aim of the investigation was to validate a high-performance liquid chromatography (HPLC) assay for routine applications.

机译：背景：异琥珀唑唑是一种用于治疗侵袭性曲曲斑和粘膜菌病的三唑抗真菌剂。目前，目前尚不清楚必需的异戊酰唑的治疗药物监测（TDM）。研究的目的是验证常规应用的高效液相色谱（HPLC）测定。

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来源
《Therapeutic Drug Monitoring》 |2018年第4期|共4页
作者
Mueller Silke C.; Karasch Ilona; Lakner Johannes; Wacke Rainer;
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作者单位

Univ Med Rostock Inst Clin Pharmacol Ctr Pharmacol &

Toxicol Rostock Germany;

Univ Med Rostock Inst Clin Pharmacol Ctr Pharmacol &

Toxicol Rostock Germany;

Univ Med Rostock Clin Hematol &

Oncol Ctr Internal Med Rostock Germany;

Univ Med Rostock Inst Clin Pharmacol Ctr Pharmacol &

Toxicol Rostock Germany;

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原文格式 PDF
正文语种 eng
中图分类生药学（天然药物学）;
关键词
isavuconazole; HPLC; therapeutic drug monitoring; hematopoietic stem cell transplantation;

机译：异琥珀唑唑;HPLC;治疗药物监测;造血干细胞移植;

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1. Validation of an Isavuconazole High-Performance Liquid Chromatography Assay in Plasma for Routine Therapeutic Drug Monitoring Applications [J] . Mueller Silke C., Karasch Ilona, Lakner Johannes, Therapeutic Drug Monitoring . 2018,第4期

机译：验证血浆中血浆中常规治疗药物监测应用中的血浆中高效液相色谱法测定
2. Quantification of sunitinib and n-desethyl sunitinib in human edta plasma by liquid chromatography coupled with electrospray ionization tandem mass spectrometry: Validation and application in routine therapeutic drug monitoring [J] . LankheetN.A.G., SteeghsN., RosingH., Therapeutic Drug Monitoring . 2013,第2期

机译：液相色谱与电喷雾电离串联质谱联用对人乙达血浆中舒尼替尼和正去乙基舒尼替尼的定量：在常规治疗药物监测中的验证和应用
3. Plasma indomethacin assay using high-performance liquid chromatography-electrospray-tandem mass spectrometry: application to therapeutic drug monitoring and pharmacokinetic studies. [J] . Taylor PJ, Jones CE, Dodds HM, Therapeutic Drug Monitoring . 1998,第6期

机译：使用高效液相色谱-电喷雾串联质谱法测定血浆消炎痛：在治疗药物监测和药代动力学研究中的应用。
4. Validation of Isoniazid for Therapeutic Drug Monitoring in Human Plasma by High-Performance Liquid Chromatography [C] . S.P.V.D. Jaikishin, D.A. Perwitasari, E. Darmawan, Conference on Fundamental and Applied Science for Advanced Technology . 2016

机译：高效液相色谱法验证人血浆治疗药物监测
5. Development and validation of a reversed-phase high-performance liquid chromatography method for polymixin B in plasma. [D] . Shah, Koshaben. 2011

机译：血浆中多粘菌素B的反相高效液相色谱方法的开发和验证。
6. Quantification of imatinib in human serum: validation of a high-performance liquid chromatography-mass spectrometry method for therapeutic drug monitoring and pharmacokinetic assays [O] . Vinicius Marcondes Rezende, Ariane Rivellis, Mafalda Megumi Yoshinaga Novaes, 2013

机译：人血清中伊马替尼的定量：用于治疗药物监测和药代动力学测定的高效液相色谱-质谱法的验证
7. Hasil Penilaian Sejawat Sebidang atau Peer Review dengan Judul Validation of Isoniazid for Therapeutic Drug Monitoring in Human Plasma by High-Performance Liquid Chromatography [O] . Jaikishin Sheila Priscilla Virmala Dewi, Perwitasari Dyah Aryani, Darmawan Endang, 2016

机译：同行评审同行评审结果，标题为高效液相色谱法检测异烟肼对人血浆中治疗药物监测的影响
8. Application of High-Performance Liquid Chromatography Assay for MonitoringKinetics of Interconversions of Stereoisomers of Thymidine Glycol [R] . Vaishnav, Y. N., Kan, L. S., Swenberg, C. E. 1992

机译：高效液相色谱法在胸苷二醇立体异构体相互转化动力学监测中的应用

Validation of an Isavuconazole High-Performance Liquid Chromatography Assay in Plasma for Routine Therapeutic Drug Monitoring Applications

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