首页> 外文期刊>The journal of pain: official journal of the American Pain Society >Alcohol and Opioid Use in Chronic Pain: A Cross-Sectional Examination of Differences in Functioning Based on Misuse Status
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Alcohol and Opioid Use in Chronic Pain: A Cross-Sectional Examination of Differences in Functioning Based on Misuse Status

机译:含酒精和阿片类药物用于慢性疼痛:基于滥用状态的运作差异的横截面检查

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Opioid misuse is regularly associated with disrupted functioning in those with chronic pain. Less work has examined whether alcohol misuse may also interfere with functioning. This study examined frequency of opioid and alcohol misuse in 131 individuals (61.1% female) prescribed opioids for the treatment of chronic pain. Participants completed an anonymous survey online, consisting of measures of pain, functioning, and opioid and alcohol misuse. Cut scores were used to categorize individuals according to substance misuse status. Individuals were categorized as follows: 35.9% (n?=?47) were not misusing either opioids or alcohol, 22.9% (n?=?30) were misusing both opioids and alcohol, 38.2% (n=50) were misusing opioids alone, and only 3.0% (n?=?4) were misusing alcohol alone. A multivariate analysis of variance was performed to examine differences in pain and functioning between groups (after excluding individuals in the alcohol misuse group due to the small sample size). Group comparisons indicated that individuals who were not misusing either substance were less disabled and distressed in comparison to those who were misusing opioids alone or both opioids and alcohol. No differences were indicated between the latter 2 groups. Overall, the observed frequency of opioid misuse was somewhat higher in comparison to previous work (approximately 1 out of every 3 participants), and misuse of both alcohol and opioids was common (approximately 1 out of every 5 participants). While these data are preliminary, they do suggest that issues of substance misuse in those with chronic pain extends beyond opioids alone. PerspectiveOpioid and alcohol misuse was examined in 131 individuals prescribed opioids for chronic pain. In total, 35.9% were not misusing either, 22.9% were misusing both, 38.2% were misusing opioids, and 3.1% were misusing alcohol. Individuals not misusing either were generally less disabled and distressed compared to those misusing opioids or both.
机译:阿片类药物滥用定期与慢性疼痛中断的扰乱功能相关。较少的工作已经检查了酒精滥用是否可能会干扰运作。本研究检测了131个个体的阿片类药物和酒精滥用频率(61.1%的女性)规定的阿片类药物用于治疗慢性疼痛。参与者在网上完成了匿名调查,包括疼痛,功能和阿片类药物和酗酒的措施。削减分数用于根据物质滥用状态对个体进行分类。个体分类如下:35.9%(n?= 47)不滥用阿片类或醇,22.9%(n?= 30)滥用阿片类药物和酒精,38.2%(n = 50)单独滥用阿片类药物,只有3.0%(n?=?4)单独滥用酒精。进行多元差异分析,以检查疼痛差异和在组之间的功能(在由于样品大小的小醇滥用组中的个体之后)。群体比较表明,与单独或阿片类药物和酒精滥用阿片类药物的人相比,没有滥用任何物质的个体都不禁用和痛苦。在后两组之间没有表明差异。总体而言,与以前的工作相比(每3名参与者中的大约1个)相比,所观察到的阿片类药物误用的频率略高,并且滥用酒精和阿片类药物是常见的(每5名参与者中约有1个)。虽然这些数据是初步的,但他们确实表明,在慢性疼痛中滥用物质滥用问题仅仅超越阿片类药物。在131名慢性疼痛中,在131个个体中检测了透视和酗酒。总共35.9%并不滥用,22.9%滥用,38.2%是滥用阿片类药物,3.1%是滥用酒精。与滥用阿片类药物或两者兼而有之,不滥用的人通常较少禁用和痛苦。

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