Multivessel versus culprit lesion only percutaneous revascularization plus potential staged revascularization in patients with acute myocardial infarction complicated by cardiogenic shock: Design and rationale of CULPRIT-SHOCK trial

Thiele Holger; Desch Steffen; Piek Jan J.; Stepinska Janina; Oldroyd Keith; Serpytis Pranas; Montalescot Gilles; Noc Marko; Huber Kurt; Fuernau Georg; de Waha Suzanne; Meyer-Saraei Roza; Schneider Steffen; Windecker Stephan; Savonitto Stefano; Briggs Andrew; Torremante Patrizia; Vrints Christiaan; Schuler Gerhard; Ceglarek Uta; Thiery Joachim; Zeymer Uwe

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Multivessel versus culprit lesion only percutaneous revascularization plus potential staged revascularization in patients with acute myocardial infarction complicated by cardiogenic shock: Design and rationale of CULPRIT-SHOCK trial

机译：Multivessel与罪魁祸首病变只有经皮血运重建加上急性心肌梗死患者的潜在分阶段血运重建，通过心形成休克复杂：罪魁祸首 - 休克试验的设计和理论

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Background In acute myocardial infarction complicated by cardiogenic shock (CS), up to 80% of patients present with multivessel coronary artery disease. Currently, the best revascularization strategy is unknown. Therefore, a prospective randomized adequately powered clinical trial is warranted.

机译：背景技术在急性心肌梗死中，通过心形成休克（CS）复杂，高达80％的患者患有多血糖冠状动脉疾病。目前，最好的血运重建策略是未知的。因此，保证了一项预期随机化的可随机通量的临床试验。

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《The American heart journal》 |2016年第null期|共10页
作者
Thiele Holger; Desch Steffen; Piek Jan J.; Stepinska Janina; Oldroyd Keith; Serpytis Pranas; Montalescot Gilles; Noc Marko; Huber Kurt; Fuernau Georg; de Waha Suzanne; Meyer-Saraei Roza; Schneider Steffen; Windecker Stephan; Savonitto Stefano; Briggs Andrew; Torremante Patrizia; Vrints Christiaan; Schuler Gerhard; Ceglarek Uta; Thiery Joachim; Zeymer Uwe;
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作者单位

Univ Heart Ctr Luebeck Lubeck Germany;

Univ Heart Ctr Luebeck Lubeck Germany;

Univ Amsterdam Acad Med Ctr Meibergdreef 9 NL-1105 AZ Amsterdam Netherlands;

Inst Cardiol Warsaw Poland;

Univ Amsterdam Acad Med Ctr Meibergdreef 9 NL-1105 AZ Amsterdam Netherlands;

Vilnius Univ Hosp Vilnius Lithuania;

CHU Pitie Salpetriere ACT Study Grp Paris France;

Univ Med Ctr Ljubljana Ljubljana Slovenia;

Wilhelminenspital Stadt Wien Vienna Austria;

Univ Heart Ctr Luebeck Lubeck Germany;

Univ Heart Ctr Luebeck Lubeck Germany;

Univ Heart Ctr Luebeck Lubeck Germany;

Inst Herzinforkrforsch Ludwigshafen Germany;

Univ Bern Inselspital CH-3010 Bern Switzerland;

Manzoni Hosp Lecce Italy;

Univ Glasgow Inst Hlth &

Wellbeing Glasgow Lanark Scotland;

GABO Milliarium mbH &

Co KG Munich Germany;

Univ Ziekenhuis Antwerp Antwerp Belgium;

Univ Leipzig Ctr Heart D-04109 Leipzig Germany;

Univ Leipzig Inst Lab Med D-04109 Leipzig Germany;

Inst Herzinforkrforsch Ludwigshafen Germany;

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正文语种 eng
中图分类心脏、血管（循环系）疾病;
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专利

1. Multivessel versus culprit lesion only percutaneous revascularization plus potential staged revascularization in patients with acute myocardial infarction complicated by cardiogenic shock: Design and rationale of CULPRIT-SHOCK trial [J] . Thiele Holger, Desch Steffen, Piek Jan J., The American heart journal . 2016,第Null期

机译：急性心肌梗死并发心源性休克的仅多支血管病变与仅脑血管病变加潜在分期血管重建：CULPRIT-SHOCK试验的设计和原理
2. Will CULPRIT-SHOCK change my practice? The CULPRIT-SHOCK trial: culprit lesion-only PCI vs. multivessel PCI in patients with acute myocardial infarction and cardiogenic shock [J] . Sarno Giovanna, Chieffo Alaide, Ludman Peter, EuroIntervention: journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology . 2018,第8期

机译：罪魁祸首会改变我的练习吗？罪魁祸首 - 急性心肌梗死患者罪名休克试验：仅限于患者的损伤性PCI与多血管蛋白PCI
3. New debate of revascularization strategy of non-infarct-related artery lesions in patients with ST-segment elevation myocardial infarction and cardiogenic shock: decoding the CULPRIT-SHOCK trial, not enough to challenge the current guidelines [J] . Fang Song, Qiang Wu, Xiao-Ping Chen 中华医学杂志（英文版） . 2019,第005期

机译：ST段抬高型心肌梗死和心源性休克患者非梗死相关动脉病变的血运重建策略的新争议：对CULPRIT-SHOCK试验进行解码，不足以挑战当前指南
4. Meta-analysis: The impact of thrombectomy during PCI (percutaneous coronary intervention) on mortality, re-infarction and target vessel revascularization among patients with ST elevation myocardial infarction compared with standard PCI. [D] . Martar, Martar. 2016

机译：荟萃分析：与标准PCI相比，ST抬高型心肌梗死患者在PCI（经皮冠状动脉介入治疗）期间进行血栓切除术对死亡率，再梗塞和靶血管血运重建的影响。
5. Protocol for an economic evaluation of the randomised controlled trial of culprit lesion only PCI versus immediate multivessel PCI in acute myocardial infarction complicated by cardiogenic shock: CULPRIT-SHOCK trial [O] . Zahidul Quayyum, Andrew Briggs, Jose Robles-Zurita, 2017

机译：经济评估方案对急性心肌梗死并发心源性休克的仅罪犯病变PCI与直接多支血管PCI进行随机对照试验：CULPRIT-SHOCK试验
6. Will CULPRIT-SHOCK change my practice? The CULPRIT-SHOCK trial: culprit lesion-only PCI vs. multivessel PCI in patients with acute myocardial infarction and cardiogenic shock [O] . Giovanna Sarno, Alaide Chieffo, Peter Ludman, 2018

机译：罪魁祸首会改变我的练习吗？罪魁祸首 - 仅急性心肌梗死患者的罪名休克试验：仅限于患者患者Multivessel PCI和心肌梗死

Multivessel versus culprit lesion only percutaneous revascularization plus potential staged revascularization in patients with acute myocardial infarction complicated by cardiogenic shock: Design and rationale of CULPRIT-SHOCK trial

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