A beta-lactamase-producing plasmid from Neisseria gonorrhoeae carrying a unique 6 bp deletion in bla(TEM-1) encoding a truncated 24 kDa TEM-1 penicillinase that hydrolyses ampicillin slowly

Singh Reema; Perera Sumudu R.; Katselis George S.; Chumala Paulos; Martin Irene; Kusalik Anthony; Mitzel Kristen M.; Dillon Jo-Anne R.

首页> 外文期刊>The Journal of Antimicrobial Chemotherapy >A beta-lactamase-producing plasmid from Neisseria gonorrhoeae carrying a unique 6 bp deletion in bla(TEM-1) encoding a truncated 24 kDa TEM-1 penicillinase that hydrolyses ampicillin slowly

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A beta-lactamase-producing plasmid from Neisseria gonorrhoeae carrying a unique 6 bp deletion in bla(TEM-1) encoding a truncated 24 kDa TEM-1 penicillinase that hydrolyses ampicillin slowly

机译：来自Neisseria歌剧肽的β-内酰胺酶生产质粒，在BLA（TEM-1）中携带独特的6bp缺失（TEM-1），编码截断的24kDa Tem-1青霉素酶，慢慢地水解氨苄青霉素

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Background Seven structurally related beta-lactamase-producing plasmids have been characterized in penicillinase-producing Neisseria gonorrhoeae (PPNG) isolates. We characterized a variant (i.e. pJRD20, Canada type) of the Africa-type (pJD5) plasmid isolated from N. gonorrhoeae strain 8903.

机译：背景技术七种结构相关的β-内酰胺酶的质粒已经表征了生成的发酵素酶的奈良菌（PPNG）分离株。我们的特征在于非洲型（PJD5）质粒的变体（即PJRD20，加拿大型）从N.淋病菌株8903中分离出来。

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《The Journal of Antimicrobial Chemotherapy》 |2019年第10期|共9页
作者
Singh Reema; Perera Sumudu R.; Katselis George S.; Chumala Paulos; Martin Irene; Kusalik Anthony; Mitzel Kristen M.; Dillon Jo-Anne R.;
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作者单位

Univ Saskatchewan Dept Biochem Microbiol &

Immunol 2D01 Hlth Sci Bldg 107 Wiggins Rd Saskatoon;

Univ Saskatchewan Dept Biochem Microbiol &

Immunol 2D01 Hlth Sci Bldg 107 Wiggins Rd Saskatoon;

Univ Saskatchewan Div Canadian Ctr Hlth &

Safety Agr Dept Med 1246 Hlth Sci E Wing 104 Clinic Pl;

Univ Saskatchewan Div Canadian Ctr Hlth &

Safety Agr Dept Med 1246 Hlth Sci E Wing 104 Clinic Pl;

Publ Hlth Agcy Canada Streptococcus &

STI Unit Natl Microbiol Lab 1015 Arlington St Winnipeg;

Univ Saskatchewan Dept Comp Sci 176 Thorvaldson Bldg 110 Sci Pl Saskatoon SK S7N 5C9 Canada;

Univ Saskatchewan Dept Biochem Microbiol &

Immunol 2D01 Hlth Sci Bldg 107 Wiggins Rd Saskatoon;

Univ Saskatchewan Dept Biochem Microbiol &

Immunol 2D01 Hlth Sci Bldg 107 Wiggins Rd Saskatoon;

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正文语种 eng
中图分类治疗学;
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1. A beta-lactamase-producing plasmid from Neisseria gonorrhoeae carrying a unique 6 bp deletion in bla(TEM-1) encoding a truncated 24 kDa TEM-1 penicillinase that hydrolyses ampicillin slowly [J] . Singh Reema, Perera Sumudu R., Katselis George S., The Journal of Antimicrobial Chemotherapy . 2019,第10期

机译：来自Neisseria歌剧肽的β-内酰胺酶生产质粒，在BLA（TEM-1）中携带独特的6bp缺失（TEM-1），编码截断的24kDa Tem-1青霉素酶，慢慢地水解氨苄青霉素
2. Prevalence of bla TEM-220 gene in Penicillinase-producing Neisseria gonorrhoeae strains carrying Toronto/Rio plasmid in Argentina, 2002 – 2011 [J] . Ricardo Gianecini, Claudia Oviedo, Cristina Guantay, BMC Infectious Diseases . 2015,第1期

机译：2002-2011年，阿根廷携带多伦多/里奥质粒的生产青霉素酶的淋病奈瑟氏球菌中bla TEM-220基因的流行率
3. Further evidence of plasmid-encoded bla-(CTX-M-15) and bla-(TEM-1) genes in Lebanese isolates of Salmonella enterica serovar Typhimurium that produce extended-spectrum beta-lactamase. [J] . Matar GM, Khairallah MT, Dandache Annals of tropical medicine and parasitology . 2010,第1期

机译：产生肠沙门氏菌血清型鼠伤寒沙门氏菌的黎巴嫩分离株中质粒编码的bla-（CTX-M-15）和bla-（TEM-1）基因的进一步证据，可产生广谱β-内酰胺酶。
4. Prevalence of blaTEM-220 gene in Penicillinase-producing Neisseria gonorrhoeae strains carrying Toronto/Rio plasmid in Argentina 2002 – 2011 [O] . Ricardo Gianecini, Claudia Oviedo, Cristina Guantay, 2015

机译：阿根廷2002年至2011年携带多伦多/里奥质粒的产青霉素酶淋病奈瑟氏球菌菌株中blaTEM-220基因的流行
5. Prevalence of bla TEM-220 gene in Penicillinase-producing Neisseria gonorrhoeae strains carrying Toronto/Rio plasmid in Argentina, 2002 – 2011 [O] . Ricardo Gianecini, Claudia Oviedo, Cristina Guantay, 2015

机译：2002-2011年，阿根廷携带多伦多/里奥质粒的生产青霉素酶的淋病奈瑟氏球菌中bla TEM-220基因的流行率

A beta-lactamase-producing plasmid from Neisseria gonorrhoeae carrying a unique 6 bp deletion in bla(TEM-1) encoding a truncated 24 kDa TEM-1 penicillinase that hydrolyses ampicillin slowly

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