Reduction of Irritation Potential Caused by Anionic Surfactants in the Use of Various Forms of Collagen Derived from Marine Sources in Cosmetics for Children

摘要

Surfactants, which are the basic ingredients in washing cosmetics, can cause skin irritation. In the case of washing cosmetics intended for children, it is necessary to select the composition in such a way as to ensure maximum reduction or even elimination of the irritant effect of the final product. The paper attempts to improve the safety of bath cosmetics for children by introducing: collagen amino acids (150 Da), hydrolysed collagen (12000 Da) and soluble collagen (300 000 Da). Zein value, bovine albumin, and human keratinocyte cell line studies have shown a significant decrease in the irritant potential of the compositions following the introduction of the proposed additives, which is more pronounced with the increase in the molecular weight of marine collagen. An important part of this work is a mechanism proposed by the authors, according to which the addition of the proposed additives can increase safety of the application of cosmetics for children.