Preventing Infection Post Hematopoietic Cell Transplantation

摘要

Hematopoietic cell transplantation (HCT) is the transfer of hematopoietic stem cells and progenitor cells from one donor to another (allogeneic) or the harvesting of cells from a patient that are then returned to that patient (autologous).1 The first successful bone marrow transplant, which took place more than six decades ago, involved the transfer of healthy bone marrow from one identical twin to the other twin, who had leukemia. Since the discovery of HCT in 1956, thousands of patients each year with various hematologic cancers and noncancerous conditions affecting the blood or bone marrow have benefited from this treatment.2 Some of the more