AB42 Oligomer Heterogeneity as an Origin for Amyloid Fibril Polymorphism

Xue Christine; Guo Zhefeng; Tran Joyce; Wang Hongsu; Hsu Frederick

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AB42 Oligomer Heterogeneity as an Origin for Amyloid Fibril Polymorphism

机译：AB42低聚物异质性作为淀粉样蛋白原纤维多态性的起源

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来源
《Protein Science: A Publication of the Protein Society》 |2018年第s1期|共1页
作者
Xue Christine; Guo Zhefeng; Tran Joyce; Wang Hongsu; Hsu Frederick;
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Univ Calif Los Angeles Los Angeles CA USA;

Univ Calif Los Angeles Los Angeles CA USA;

Univ Calif Los Angeles Los Angeles CA USA;

Univ Calif Los Angeles Los Angeles CA USA;

Univ Calif Los Angeles Los Angeles CA USA;

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原文格式 PDF
正文语种 eng
中图分类生物化学;
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专利

1. AB42 Oligomer Heterogeneity as an Origin for Amyloid Fibril Polymorphism [J] . Xue Christine, Guo Zhefeng, Tran Joyce, Protein Science: A Publication of the Protein Society . 2018,第S1期

机译：AB42低聚物异质性作为淀粉样蛋白原纤维多态性的起源
2. Development of the structural core and of conformational heterogeneity during the conversion of oligomers of the mouse prion protein to worm-like amyloid fibrils [J] . SinghJ., SabareesanA.T., MathewM.K., Journal of Molecular Biology . 2012,第2期

机译：小鼠病毒蛋白的低聚物转化为蠕虫状淀粉样蛋白原纤维过程中结构核心和构象异质性的发展
3. Fibril specific, conformation dependent antibodies recognize a generic epitope common to amyloid fibrils and fibrillar oligomers that is absent in prefibrillar oligomers [J] . Rakez Kayed, Elizabeth Head, Floyd Sarsoza, Molecular neurodegeneration . 2007,第1期

机译：原纤维特异性，构象依赖性抗体识别淀粉样原纤维和原纤维寡聚体中不存在的通用表位
4. Monitoring the Proteolytic Degradation of β-2-Microglobulin Oligomers and Amyloid Fibrils using Mass Spectrometry [C] . William J. Warren, Jill Graham, Peter Chien, ASMS Conference on Mass Spectrometry and Allied Topics . 2014

机译：使用质谱法监测β-2微粒蛋白低聚物和淀粉样蛋白原纤维的蛋白水解降解
5. A study of coevolved, cofolding and functionally linked proteins and the characterization of amyloid-like fibrils and oligomers towards the understanding of protein aggregation in disease. [D] . Teng, Poh Kheng. 2010

机译：共同进化，共同折叠和功能连接的蛋白质的研究以及淀粉样蛋白样原纤维和寡聚物的表征，旨在了解疾病中的蛋白质聚集。
6. Aβ42 fibril formation from predominantly oligomeric samples suggests a link between oligomer heterogeneity and fibril polymorphism [O] . Christine Xue, Joyce Tran, Hongsu Wang, 2019

机译：主要由寡聚样品形成的Aβ42原纤维表明寡聚物异质性与原纤维多态性之间存在联系
7. Alzheimer's Ab42 oligomers but not fibrils simultaneously bind to and cause damage to ganglioside containing lipid membranes [O] . Willliams Thomas L, Johnson Benjamin R.G, Urbanc Brigita, 2011

机译：阿尔茨海默氏症的Ab42低聚物同时不与原纤维同时结合，并导致含有神经节苷脂的脂质膜受损

AB42 Oligomer Heterogeneity as an Origin for Amyloid Fibril Polymorphism

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