Inline monitoring of the powder filling level within a rotary tablet press feed frame update

摘要

The filling level within feed frames and the uniformity of the powder supply by feed frames for die filling have not been monitored so far during tableting processes. This study was intended to investigate if the powder filling level inside a rotary tablet press feed frame is affected by the feed frames' paddle wheel speed and/or by the turret speed. Furthermore, it was examined whether the filling level affects the resulting tablet masses while filling the respective dies. Two tableting excipients one with poor flowability and one with excellent flowability were selected as model powders.