The value of time-to-onset in statistical signal detection of adverse drug reactions: a comparison with disproportionality analysis in spontaneous reports from the Netherlands

Scholl Joep H. G.; van Puijenbroek Eugene P.

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The value of time-to-onset in statistical signal detection of adverse drug reactions: a comparison with disproportionality analysis in spontaneous reports from the Netherlands

机译：不良药物反应统计信号检测中的时间到上的值：与荷兰的自发报告中的不成比率分析比较

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Purpose In pharmacovigilance, the commonly used disproportionality analysis (DPA) in statistical signal detection is known to have its limitations. The aim of this study was to investigate the value of the time to onset (TTO) of ADRs in addition to DPA.

机译：目的在药物检测中，已知统计信号检测中的常用歧化性分析（DPA）具有其限制。本研究的目的是研究除DPA之外，还研究ADR的时间（TTO）的价值。

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来源
《Pharmacoepidemiology and drug safety》 |2016年第12期|共7页
作者
Scholl Joep H. G.; van Puijenbroek Eugene P.;
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作者单位

Netherlands Pharmacovigilance Ctr Lareb Goudsbloemvallei 7 NL-5237 MH Shertogenbosch Netherlands;

Netherlands Pharmacovigilance Ctr Lareb Goudsbloemvallei 7 NL-5237 MH Shertogenbosch Netherlands;

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原文格式 PDF
正文语种 eng
中图分类药学;
关键词
signal detection; time to onset; latency; pharmacovigilance; ADR; pharmacoepidemiology;

机译：信号检测;发起的时间;延迟;药物检测;ADR;药物杂散学;

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1. The value of time-to-onset in statistical signal detection of adverse drug reactions: a comparison with disproportionality analysis in spontaneous reports from the Netherlands [J] . Scholl Joep H. G., van Puijenbroek Eugene P. Pharmacoepidemiology and drug safety . 2016,第12期

机译：发病时间在药物不良反应的统计信号检测中的价值：与荷兰自发报告中的不成比例分析进行比较
2. A comparison of measures of disproportionality for signal detection on adverse drug reaction spontaneous reporting database of Guangdong province in China. [J] . Li C, Xia J, Deng J, Pharmacoepidemiology and drug safety . 2008,第6期

机译：中国广东省药品不良反应自发报告数据库信号检测不成比例措施的比较。
3. Data mining spontaneous adverse drug event reports for safety signals in Singapore - a comparison of three different disproportionality measures [J] . Ang Pei San, Chen Zhaojin, Chan Cheng Leng, Expert opinion on drug safety . 2016,第5期

机译：数据挖掘自发性不良药物事件报告，以获取新加坡的安全信号-三种不同失衡措施的比较
4. A Systematic Prediction of Adverse Drug Reactions Using Pre-clinical Drug Characteristics and Spontaneous Reports [C] . Ngufor Che, Wojtusiak Janusz, Pathak Jyotishman IEEE International Conference on Healthcare Informatics . 2015

机译：利用临床前药物特性和自发报告对药物不良反应进行系统的预测
5. Signal Detection of Adverse Drug Reaction using the Adverse Event Reporting System: Literature Review and Novel Methods [D] . Pham, Minh H. 2018

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The value of time-to-onset in statistical signal detection of adverse drug reactions: a comparison with disproportionality analysis in spontaneous reports from the Netherlands

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