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首页> 外文期刊>Pharmacoepidemiology and drug safety >Alcohol consumption among Canadians taking benzodiazepines and related drugs.
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Alcohol consumption among Canadians taking benzodiazepines and related drugs.

机译:加拿大人服用苯二氮藻和相关药物的酒精消费。

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PURPOSE: Benzodiazepines and related drugs (BZDs) are widely used for the treatment of anxiety, insomnia and other conditions. The combination of BZDs with alcohol increases risk for oversedation, abuse, dependence and accidents. This study examines drinking behaviour among Canadians taking BZDs. METHODS: We use data from cycle 1.2 of the Canadian Community Health Survey, a large (n = 36,984) population survey conducted in 2002 by Statistics Canada. We use bivariate methods and logistic regression to test the independent association between BZD use and 2 levels of recent drinking in the general population, and then examine associations between drinking and sociodemographic factors within the group of BZD users. RESULTS: Any drinking and heavy drinking are less common among users of BZDs than among other respondents, but these differences are small (any drinking, OR = 0.77, p = 0.02; heavy drinking, OR = 0.81, p = 0.13) when differences in respondent characteristics are controlled statistically. Among BZD users, any drinking is associated with male sex, younger age and not meeting criteria for a past-year anxiety disorder. Heavy drinking is associated only with younger age. CONCLUSIONS: Heavy alcohol use is uncommon among users of BZDs, and the combination of alcohol and BZD use is rare in the general population. Differences between BZD users and others are not large when other factors are taken into account, however, which may call into question the effectiveness of physician and pharmacist warnings against this combination. People treated for an anxiety disorder with BZDs may be less likely to use alcohol than those taking them for other indications.
机译:目的:苯并二氮卓和相关药物(BZDS)被广泛用于治疗焦虑,失眠和其他条件。 BZDS与酒精的结合增加了过度努力,虐待,依赖和事故的风险。本研究审查了加拿大人采取BZD的饮酒行为。方法:我们使用加拿大社区卫生调查的周期1.2的数据,通过加拿大统计,2002年进行的大(n = 36,984)人口调查。我们使用Bivariate方法和Logistic回归来测试BZD使用与一般人群最近饮酒之间的独立关联,然后审查BZD用户组中的饮酒和社会淘气因子之间的关联。结果:任何饮酒和重度饮酒都不常见于BZDS的用户,而不是其他受访者,但这些差异很小(任何饮用,或= 0.77,P = 0.02;倍数饮酒,或= 0.81,P = 0.13)受访者特征在统计上控制。在BZD用户中,任何饮酒都与男性性别,较小的年龄较小,而不是达到过去一年焦虑症的标准。沉重的饮酒仅与年龄较小。结论:BZDS的用户中,重质醇类使用罕见,醇和BZD使用的组合在一般人群中很少见。然而,当考虑其他因素时,BZD用户与其他人之间的差异并不大,这可能调查了医生和药剂师警告对此组合的有效性。用BZDS治疗焦虑症的人可能不太可能使用酒精,而不是那些服用其他适应症的人。

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