TEZACAFTOR/IVACAFTOR IMPROVES CFTR FUNCTION IN CELLS FROM F508DEL-L927P HETEROZYGOTES

Brown C. D.; Ostmann A.; Strecker L. M.; Howenstine M.; Ray K.; Brewington J. J.

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TEZACAFTOR/IVACAFTOR IMPROVES CFTR FUNCTION IN CELLS FROM F508DEL-L927P HETEROZYGOTES

机译：Tezacaftor / IVAcaftor改善了来自F508DEL-L927P杂合子的细胞中的CFTR功能

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来源
《Pediatric Pulmonology》 |2018年第2期|共1页
作者
Brown C. D.; Ostmann A.; Strecker L. M.; Howenstine M.; Ray K.; Brewington J. J.;
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作者单位

Indiana Univ Indianapolis IN 46204 USA;

Cincinnati Childrens Hosp Cincinnati OH USA;

Cincinnati Childrens Hosp Cincinnati OH USA;

Indiana Univ Indianapolis IN 46204 USA;

Cincinnati Childrens Hosp Cincinnati OH USA;

Cincinnati Childrens Hosp Cincinnati OH USA;

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原文格式 PDF
正文语种 eng
中图分类儿科学;
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入库时间 2022-08-20 06:04:11

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专利

1. TEZACAFTOR/IVACAFTOR IMPROVES CFTR FUNCTION IN CELLS FROM F508DEL-L927P HETEROZYGOTES [J] . Brown C. D., Ostmann A., Strecker L. M., Pediatric Pulmonology . 2018,第Suppla2期

机译：Tezacaftor / IVAcaftor改善了来自F508DEL-L927P杂合子的细胞中的CFTR功能
2. RETROSPECTIVE ANALYSIS OF PHYSIOLOGICAL RESPONSE PATTERNS TO TEZACAFTOR/IVACAFTOR IN PATIENTS WITH CYSTIC FIBROSIS HOMOZYGOUS FOR F508DEL-CFTR OR HETEROZYGOUS FOR F508DEL-CFTR AND A RESIDUAL FUNCTION MUTATION [J] . Ingenito E., Nair N., Yi B., Thorax: The Journal of the British Thoracic Society . 2018,第Suppla4期

机译：对F508DEL-CFTR纯合型囊性纤维化患者的生理反应模式对Tezacafetor / Ivacafacter的回顾性分析，或者F508del-CFTR的杂合和残余功能突变
3. RETROSPECTIVE ANALYSIS OF PHYSIOLOGICAL RESPONSE PATTERNS TO TEZACAFTOR/IVACAFTOR IN PATIENTS WITH CYSTIC FIBROSIS HOMOZYGOUS FOR F508DEL-CFTR OR HETEROZYGOUS FOR F508DEL-CFTR AND A RESIDUAL FUNCTION MUTATION [J] . Ingenito E., Nair N., Yi B., Pediatric Pulmonology . 2018,第Suppla2期

机译：对F508DEL-CFTR纯合型囊性纤维化患者的生理反应模式对Tezacafetor / Ivacafacter的回顾性分析，或者F508del-CFTR的杂合和残余功能突变
4. NEW PHARMACOLOGICAL TARGETS FOR CYSTIC FIBROSIS TREATMENT FROM EXTENSIVE PROTEOMIC PROFILING OF ?F508-CFTR EXPRESSING CELLS [C] . Clarissa Braccia, Valeria Tomati, Nicoletta Pedemonte, International Mass Spectrometry Conference . 2018

机译：新的药理纤维化治疗来自αF508-CFTR的广泛蛋白质组学分析
5. Coexpression of mutant forms of CFTR inhibit wild-type CFTR expression and function in airway epithelium. [D] . Tucker, Torry Alle. 2004

机译：CFTR突变形式的共表达抑制气道上皮中的野生型CFTR表达和功能。
6. Treatment of Cystic Fibrosis Patients Homozygous for F508del with Lumacaftor-Ivacaftor (Orkambi®) Restores Defective CFTR Channel Function in Circulating Mononuclear Cells [O] . Maria Favia, Crescenzio Gallo, Lorenzo Guerra, 2020

机译：用Lumacaftor-Ivacaftor（Orkambi®）治疗F508del纯合的囊性纤维化患者恢复循环单核细胞中CFTR通道功能的缺陷。
7. Tezacaftor–Ivacaftor in Residual-Function Heterozygotes with Cystic Fibrosis [O] . Rowe, Steven M., Daines, Cori, Ringshausen, Felix C., 2017

机译：Tezacaftor–Ivacaftor在囊性纤维化的残留功能杂合子中的作用

TEZACAFTOR/IVACAFTOR IMPROVES CFTR FUNCTION IN CELLS FROM F508DEL-L927P HETEROZYGOTES

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