Slow wave activity and executive dysfunction in children with sleep disordered breathing

摘要

Purpose This study aimed to examine slow wave activity (SWA), a marker of homeostatic regulation, as a potential mechanism linking sleep disordered breathing (SDB) with executive dysfunction in children. Methods Executive function domains of working memory, spatial planning, information processing, and sustained attention were assessed using the Cambridge Neuropsychological Test Automated Battery (CANTAB) in children ( N ?=?40; 5–12?years) referred for clinical diagnosis of SDB. Polysomnography records of non-snoring, age-matched controls ( N ?=?34) were retrospectively examined for comparison of SWA. Power spectral analysis of the delta wave determined SWA. Group differences in sleep, respiratory, and SWA outcomes were examined. Mean CANTAB scores were compared to standardized norms and correlated against SWA. Results Children with SDB showed increased SWA compared to non-snoring controls and scored