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Bayesian adaptive lasso for additive hazard regression with current status data

机译:Bayesian Adaptive Lasso用于附加危险回归与当前状态数据

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摘要

Variable selection is a crucial issue in model building and it has received considerable attention in the literature of survival analysis. However, available approaches in this direction have mainly focused on time‐to‐event data with right censoring. Moreover, a majority of existing variable selection procedures for survival models are developed in a frequentist framework. In this article, we consider additive hazards model in the presence of current status data. We propose a Bayesian adaptive least absolute shrinkage and selection operator procedure to conduct a simultaneous variable selection and parameter estimation. Efficient Markov chain Monte Carlo methods are developed to implement posterior sampling and inference. The empirical performance of the proposed method is demonstrated by simulation studies. An application to a study on the risk factors of heart failure disease for type 2 diabetes patients is presented.
机译:变量选择是模型建设中的一个至关重要的问题,在生存分析的文献中受到了相当大的关注。 但是,此方向上的可用方法主要集中在与右审查的事件时间数据上。 此外,在频繁的框架中开发了用于生存模型的大多数现有变量选择程序。 在本文中,我们考虑在存在当前状态数据的情况下的添加剂危险模型。 我们提出了贝叶斯自适应最不绝对的收缩和选择操作员程序,以进行同时变量选择和参数估计。 高效的马尔可夫链蒙特卡罗方法是开发的,以实现后部采样和推理。 通过模拟研究证明了所提出的方法的经验性能。 介绍了2型糖尿病患者心力衰竭疾病危险因素的研究。

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