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Comparing a multivariate response Bayesian random effects logistic regression model with a latent variable item response theory model for provider profiling on multiple binary indicators simultaneously

机译:将多元响应贝叶斯随机效应逻辑回归模型与潜在的变量响应理论模型同时在多个二进制指标上的提供商分析

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Provider profiling entails comparing the performance of hospitals on indicators of quality of care. Many common indicators of healthcare quality are binary (eg, short‐term mortality, use of appropriate medications). Typically, provider profiling examines the variation in each indicator in isolation across hospitals. We developed Bayesian multivariate response random effects logistic regression models that allow one to simultaneously examine variation and covariation in multiple binary indicators across hospitals. Use of this model allows for (i) determining the probability that a hospital has poor performance on a single indicator; (ii) determining the probability that a hospital has poor performance on multiple indicators simultaneously; (iii) determining, by using the Mahalanobis distance, how far the performance of a given hospital is from that of an average hospital. We illustrate the utility of the method by applying it to 10?881 patients hospitalized with acute myocardial infarction at 102 hospitals. We considered six binary patient‐level indicators of quality of care: use of reperfusion, assessment of left ventricular ejection fraction, measurement of cardiac troponins, use of acetylsalicylic acid within 6?hours of hospital arrival, use of beta‐blockers within 12?hours of hospital arrival, and survival to 30?days after hospital admission. When considering the five measures evaluating processes of care, we found that there was a strong correlation between a hospital's performance on one indicator and its performance on a second indicator for five of the 10 possible comparisons. We compared inferences made using this approach with those obtained using a latent variable item response theory model.
机译:提供商分析需要比较医院对护理质量指标的表现。许多常见的医疗质量指标是二进制的(例如,短期死亡率,使用适当的药物)。通常,提供商分析在医院隔离中检查每个指标的变化。我们开发了贝叶斯多变量响应随机效应逻辑回归模型,其允许同时检查多个二进制指标的变化和协变量。使用此模型允许(i)确定医院在单个指标上表现不佳的概率; (ii)确定医院同时在多个指标上表现不佳的可能性; (iii)通过使用Mahalanobis距离来确定给定医院的性能来自普通医院的表现。我们通过将其施加到102名医院住院的10患者881名患者来说明该方法的效用。我们考虑了六个二元患者水平的护理级指标:使用再灌注,左心室喷射分数的评估,心肌肌钙蛋白的测量,在6?小时内使用乙酰胱氨酸酸,在12?小时内使用β-opleters医院到达,生存到30次入院后的30天。在考虑评估护理程序的五项措施时,我们发现医院在一个指标的表现与第二个指标的性能之间存在强烈的相关性,其中5个可能的比较的五个。我们比较了使用这种方法的推论与使用潜在可变项目响应理论模型获得的那些。

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