Novel fork-tip needles versus standard needles for EUS-guided tissue acquisition from solid masses of the upper GI tract: a matched cohort study

摘要

Background: There are very few available data on the novel SharkCore needles for EUS-FNB.Aim: Comparison of the performance of the SharkCore needles with the standard EUS-FNA needles for the diagnosis of solid upper GI masses.Patients and methods: Single-center, retrospective cohort study in an academic tertiary referral hospital. Patients were matched 1:1 for the site of the lesion and the presence or absence of rapid on-site evaluation (ROSE).Results: A total of 102 patients were included. There was no statistically significant difference in the mean number of passes (3.31.3 versus 3.41.5; p=.89). Similar results were observed at the subgroup with ROSE (4.3 +/- 1.3 versus 3.7 +/- 1.5; p=.26). More histological specimens were obtained with the SharkCore needles compared to standard needles (59 versus 5%; p .05 in all cases). At multivariable analysis, there was no statistically significant difference in the mean number of passes in all patients (p=.23) and in the ROSE subgroup (p=.66). However, the SharkCore needle obtained significantly more histological material than the standard needle (odds ratio 66; 95% confidence interval: 11.8, 375.8, p<.001). There was no significant difference in complication rates (p=.5).Limitations: Retrospective study, single-center.Conclusion: The SharkCore needles were similar to standard FNA needles in terms of the number of passes to reach diagnosis, but obtained significantly more histological specimen.