Anti-parietal cell autoimmunity is associated with an accelerated decline of lung function in IPF patients

Beltramo Guillaume; Thabut Gabriel; Peron Nicolas; Nicaise Pascale; Cazes Aurelie; Debray Marie-Pierre; Joannes Audrey; Castier Yves; Mailleux Arnaud A.; Frija Justine; Pradere Pauline; Justet Aurelien; Borie Raphael; Dombret Marie-Christine; Taille Camille; Aubier Michel; Crestani Bruno

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Anti-parietal cell autoimmunity is associated with an accelerated decline of lung function in IPF patients

机译：抗顶细胞自身免疫与IPF患者肺功能的加速下降有关

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Background: Autoantibodies against lung epithelial antigens are often detected in patients with Idiopathic Pulmonary Fibrosis (IPF). Anti-Parietal Cell Antibodies (APCA) target the H+/K+ ATPase (proton pump). APCA prevalence and lung H+/K+ ATPase expression was never studied in IPF patients.

机译：背景：对特发性肺纤维化（IPF）的患者通常检测到针对肺上皮抗原的自身抗体。抗顶细胞抗体（APCA）靶向H + / K + ATP酶（质子泵）。在IPF患者中从未研究过APCA患病率和肺部H + / K + ATP酶表达。

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来源
《Respiratory medicine》 |2018年第2018期|共7页
作者
Beltramo Guillaume; Thabut Gabriel; Peron Nicolas; Nicaise Pascale; Cazes Aurelie; Debray Marie-Pierre; Joannes Audrey; Castier Yves; Mailleux Arnaud A.; Frija Justine; Pradere Pauline; Justet Aurelien; Borie Raphael; Dombret Marie-Christine; Taille Camille; Aubier Michel; Crestani Bruno;
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作者单位

Hop Bichat Claude Bernard Serv Pneumol A AP HP DHU FIRE Fibrosis Inflammat &

Remodeling F-75018;

Hop Bichat Claude Bernard AP HP Serv Pneumol &

Transplantat F-75018 Paris France;

Hop Bichat Claude Bernard Serv Pneumol A AP HP DHU FIRE Fibrosis Inflammat &

Remodeling F-75018;

Hop Bichat Claude Bernard Dept Hematol &

Immunol UF Autoimmunite &

Hypersen AP HP F-75018 Paris;

Labex Inflamex INSERM UMR 1152 Paris France;

Hop Bichat Claude Bernard Serv Radiol AP HP Paris France;

Labex Inflamex INSERM UMR 1152 Paris France;

Labex Inflamex INSERM UMR 1152 Paris France;

Labex Inflamex INSERM UMR 1152 Paris France;

Univ Paris Diderot Paris France;

Hop Bichat Claude Bernard Serv Pneumol A AP HP DHU FIRE Fibrosis Inflammat &

Remodeling F-75018;

Hop Bichat Claude Bernard Serv Pneumol A AP HP DHU FIRE Fibrosis Inflammat &

Remodeling F-75018;

Hop Bichat Claude Bernard Serv Pneumol A AP HP DHU FIRE Fibrosis Inflammat &

Remodeling F-75018;

Hop Bichat Claude Bernard Serv Pneumol A AP HP DHU FIRE Fibrosis Inflammat &

Remodeling F-75018;

Hop Bichat Claude Bernard Serv Pneumol A AP HP DHU FIRE Fibrosis Inflammat &

Remodeling F-75018;

Hop Bichat Claude Bernard Serv Pneumol A AP HP DHU FIRE Fibrosis Inflammat &

Remodeling F-75018;

Hop Bichat Claude Bernard Serv Pneumol A AP HP DHU FIRE Fibrosis Inflammat &

Remodeling F-75018;

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原文格式 PDF
正文语种 eng
中图分类呼吸系及胸部疾病;
关键词
Idiopathic pulmonary fibrosis; Autoimmunity; Proton pump; Hydrogen / potassium ATPase;

机译：特发性肺纤维化;自身免疫;质子泵;氢/钾ATP酶;

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专利

1. Anti-parietal cell autoimmunity is associated with an accelerated decline of lung function in IPF patients [J] . Beltramo Guillaume, Thabut Gabriel, Peron Nicolas, Respiratory medicine . 2018,第期

机译：抗顶细胞自身免疫与IPF患者肺功能的加速下降有关
2. EFFECT OF BASELINE FVC ON DECLINE IN LUNG FUNCTION WITH NINTEDANIB IN PATIENTS WITH IPF: RESULTS FROM THE INPULSIS (R) TRIALS [J] . Kolb Martin, Kimura Toshio, Stowasser Susanne, Respirology : . 2015,第Suppla3期

机译：基线FVC对IPF患者使用Nintedanib的肺功能下降的影响：INPULSIS（R）试验的结果
3. Obstructive lung function decline and IPF: The dark face of the moon [J] . Carone Mauro, Salerno Francesco G., Esquinas Antonio M. Chronic respiratory disease. . 2016,第2期

机译：阻塞性肺功能下降和IPF：月亮的黑脸
4. Hyperpolarized Gas Magnetic Resonance Imaging Texture Analysis and Machine Learning to explain Accelerated Lung Function Decline in Ex-smokers with and without COPD [C] . Maksym Sharma, Andrew Westcott, David G McCormack, Conference on Medical Imaging: Biomedical Applications in Molecular, Structural, and Functional Imaging . 2021

机译：超极化气体磁共振成像纹理分析和机器学习解释了在吸烟者的加速肺功能下降，没有COPD
5. Modeling Dose-Function Response and Toxicity Pathways in Non-Small Cell Lung Cancer Patients Undergoing Radiation Treatment [D] . Owen, Daniel Rockwell. 2021

机译：非小细胞肺癌患者辐射治疗中的剂量函数响应和毒性途径
6. CA 19-9 serum levels in patients with end-stage idiopathic pulmonaryfibrosis (IPF) and other interstitial lung diseases (ILDs): Correlation withfunctional decline [O] . Elisabetta Balestro, Gioele Castelli, Nicol Bernardinello, 2020

机译：CA 19-9患有终末期特发性肺的血清水平纤维化（IPF）和其他间质肺病（ILDS）：与...相关功能衰退
7. Anti-parietal cell autoimmunity is associated with an accelerated decline of lung function in IPF patients [O] . Guillaume Beltramo, Gabriel Thabut, Nicolas Peron, 2018

机译：抗顶细胞自身免疫与IPF患者肺功能的加速下降有关

Anti-parietal cell autoimmunity is associated with an accelerated decline of lung function in IPF patients

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