Efficacy and safety of glycopyrrolate/eFlow (R) CS (nebulized glycopyrrolate) in moderate-to-very-severe COPD: Results from the glycopyrrolate for obstructive lung disease via electronic nebulizer (GOLDEN) 3 and 4 randomized controlled trials

Kerwin Edward; Donohue James F.; Goodin Thomas; Tosiello Robert; Wheeler Alistair; Ferguson Gary T.

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Efficacy and safety of glycopyrrolate/eFlow (R) CS (nebulized glycopyrrolate) in moderate-to-very-severe COPD: Results from the glycopyrrolate for obstructive lung disease via electronic nebulizer (GOLDEN) 3 and 4 randomized controlled trials

机译：中度至非常严重的COPD中糖甲酸盐/ eflow（r）cs（雾化甘氨酸）的疗效和安全性：通过电子雾化器（金色）3和4次随机对照试验的阻塞性肺病的甘吡咯醇

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Background:SUN-101 is a combination of glycopyrrolate delivered through an innovative, electronic nebulizer, intended for the treatment of patients with COPD. The objective of this study was to assess the efficacy and safety of this new drug device combination.

机译：背景：Sun-101是通过创新的电子雾化器提供的甘瓶种的组合，用于治疗COPD患者。本研究的目的是评估该新药物装置组合的疗效和安全性。

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来源
《Respiratory medicine》 |2017年第2017期|共13页
作者
Kerwin Edward; Donohue James F.; Goodin Thomas; Tosiello Robert; Wheeler Alistair; Ferguson Gary T.;
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作者单位

Southern Oregon Inc Clin Res Inst 3860 Crater Lake Ave Medford OR 97504 USA;

Univ N Carolina Sch Med Chapel Hill NC USA;

Sunovion Pharmaceut Inc Marlborough MA USA;

Sunovion Pharmaceut Inc Marlborough MA USA;

Sunovion Pharmaceut Inc Marlborough MA USA;

Pulm Res Inst Southeast Michigan Farmington Hills MI USA;

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原文格式 PDF
正文语种 eng
中图分类呼吸系及胸部疾病;
关键词
COPD; eFlow (R) CS; Glycopyrrolate; Maintenance; Nebulizer; SUN-101;

机译：copd;eflow（r）cs;甘瓶;维护;雾化器;太阳101;

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1. Efficacy and safety of glycopyrrolate/eFlow (R) CS (nebulized glycopyrrolate) in moderate-to-very-severe COPD: Results from the glycopyrrolate for obstructive lung disease via electronic nebulizer (GOLDEN) 3 and 4 randomized controlled trials [J] . Kerwin Edward, Donohue James F., Goodin Thomas, Respiratory medicine . 2017,第期

机译：中度至非常严重的COPD中糖甲酸盐/ eflow（r）cs（雾化甘氨酸）的疗效和安全性：通过电子雾化器（金色）3和4次随机对照试验的阻塞性肺病的甘吡咯醇
2. Efficacy and safety of a novel, nebulized glycopyrrolate for the treatment of COPD: effect of baseline disease severity and age; pooled analysis of GOLDEN 3 and GOLDEN 4 [J] . Jill Ohar, Robert Tosiello, Thomas Goodin, International Journal of Chronic Obstructive Pulmonary Disease . 2018,第4期

机译：新型雾化格隆溴铵治疗COPD的疗效和安全性：基线疾病严重程度和年龄的影响; GOLDEN 3和GOLDEN 4的汇总分析
3. Effect of background long-acting betasub2/sub-agonist therapy on the efficacy and safety of a novel, nebulized glycopyrrolate in subjects with moderate-to-very-severe COPD [J] . Edward M Kerwin, Robert Tosiello, Barry Price, International Journal of Chronic Obstructive Pulmonary Disease . 2018,第1期

机译：背景长效β_{2 激动剂疗法对新型雾化格隆溴铵在中度至重度COPD患者中的疗效和安全性的影响}
4. Randomized Controlled Trials of the Efficacy of Lung Cancer Screening by Sputum Cytology Revisited [C] . V.Paul Doria-Rose, Pamela M.Marcus, Eva Szabo, 21st international conference on screening for lung cancer . 2009

机译：再次通过痰细胞学筛查肺癌的功效的随机对照试验。
5. Predictive Biomarkers of the Efficacy of Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors in Treating Advanced Non-small Cell Lung Cancer: A Systematic Review of Randomized Controlled Trials [D] . Yang, Zuyao. 2014

机译：表皮生长因子受体酪氨酸激酶抑制剂治疗晚期非小细胞肺癌疗效的预测生物标志物：随机对照试验的系统评价。
6. Dose selection for glycopyrrolate/eFlow® phase III clinical studies: results from GOLDEN (Glycopyrrolate for Obstructive Lung Disease via Electronic Nebulizer) phase II dose-finding studies [O] . James F. Donohue, Thomas Goodin, Robert Tosiello, 2017

机译：格隆溴铵/eFlow®III期临床研究的剂量选择：GOLDEN（通过电子雾化器用于阻塞性肺疾病的格隆溴铵）II期剂量研究的结果
7. Efficacy and safety of glycopyrrolate/eFlow® CS (nebulized glycopyrrolate) in moderate-to-very-severe COPD: Results from the glycopyrrolate for obstructive lung disease via electronic nebulizer (GOLDEN) 3 and 4 randomized controlled trials [O] . Edward Kerwin, James F. Donohue, Thomas Goodin, 2017

机译：甘氨吡咯醇/EFLOW®CS（雾化甘丙烯酸盐）在中度至非常严重的COPD中的功效和安全性：通过电子雾化器（Golden）3和4试验的阻塞性肺病的甘吡咯醇类产生的结果

Efficacy and safety of glycopyrrolate/eFlow (R) CS (nebulized glycopyrrolate) in moderate-to-very-severe COPD: Results from the glycopyrrolate for obstructive lung disease via electronic nebulizer (GOLDEN) 3 and 4 randomized controlled trials

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