Dinitrophenylhydrazine: beta-cyclodextrin inclusion complex as a novel fluorescent chemosensor probe for Ce4+

摘要

An inclusion complex of 2,4-dinitrophenyl hydrazine (DNPH) with beta-cyclodextrin (beta-CD) was prepared and investigated using UV-visible and fluorescence spectral techniques in liquid states, FTIR and NMR techniques in solid state, and molecular docking techniques in virtual states. The binding constants for the formation of 1:1 DNPH: beta-CD inclusion complex are estimated by UV-visible and fluorescence spectral techniques. To study the preferred orientation of guest molecules into the host, molecular simulation studies are used. Results of computational studies, semi-empirical analysis and experimental investigations correlate well with each other. The chemosensory power of DNPH: beta-CD complex was investigated thoroughly for various metal cations and we found the emission of a complex showed a drastic increase in the intensity for Ce4+. Competition experiments of DNPH: beta-CD complex with Ce4+ in the presence of other metal ions showed that no significant variation was found in the fluorescence intensity of DNPH:-CD complex upon adding all other cations. The linearity range, LOD and LOQ are determined from the selectivity and sensitivity studies for Ce4+. Our result suggests that the DNPH: beta-CD inclusion complex would be promising material for developing a solid state sensory device for sensing Ce4+.