Trinulactones A-D, New Dinorsesterterpenoids from Streptomyces sp. S006

摘要

Four new dinorsesterterpenoids, designated as trinulactones A-D (1-4), were isolated from the Streptomyces sp. S006 strain. All the compounds contained a tricyclic skeleton, which was attached to a highly oxygenated unsaturated y-lactone. Their structures were determined by analysis of their spectroscopic data, mainly ID, 2D NMR and HR-ESIMS data. In particular, compounds 3a/3b and 4a/4b were identified individually as atropisomers.